Structural basis of Aurora-A activation by TPX2 at the mitotic spindle (Q24298490)

GOA release 2020-03-11

Aurora kinase A

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activation of protein kinase activity

GOA release 2020-03-11

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GOA release 2020-03-11

author

Elena Conti

4

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Richard Bayliss

object named as

Richard Bayliss

1

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Isabelle Vernós

object named as

Isabelle Vernos

3

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author name string

Teresa Sardon

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

2

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language of work or name

English

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publication date

October 2003

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published in

Molecular Cell

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volume

12

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page(s)

851-62

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issue

4

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cites work

1 reference

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7 January 2021

Phosphorylation of the carboxyl terminus of inner centromere protein (INCENP) by the Aurora B Kinase stimulates Aurora B kinase activity

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Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p

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Crystal structure of aurora-2, an oncogenic serine/threonine kinase

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How MAP kinases are regulated

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Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases

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Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

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Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans

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Importance of the A-helix of the catalytic subunit of cAMP-dependent protein kinase for stability and for orienting subdomains at the cleft interface

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7 January 2021

The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly

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Protein structure comparison by alignment of distance matrices

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The conformational plasticity of protein kinases

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Active and inactive protein kinases: structural basis for regulation

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Improved methods for building protein models in electron density maps and the location of errors in these models

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Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts

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The mitotic spindle: a self-made machine

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Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle

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Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

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Human TPX2 is required for targeting Aurora-A kinase to the spindle

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Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A.

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Structure of the unliganded cAMP-dependent protein kinase catalytic subunit from Saccharomyces cerevisiae

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Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA.

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Mitotic kinases as regulators of cell division and its checkpoints

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Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography

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Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors

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Importin alpha-regulated nucleation of microtubules by TPX2.

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Autoactivation of catalytic (C alpha) subunit of cyclic AMP-dependent protein kinase by phosphorylation of threonine 197

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7 January 2021

A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly

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The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation

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TPX2, A novel xenopus MAP involved in spindle pole organization

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Atomic structure of the MAP kinase ERK2 at 2.3 A resolution

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10.1016/S1097-2765(03)00392-7

Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

499268

499268

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference