Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism (Q24299210)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

SH3 domain-binding protein 2

18 January 2020

main subject

1 reference

GOA release 2020-03-11

author

Paul M Krzyzanowski

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Robert Rottapel

15

1 reference

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18 January 2020

author name string

Noam Levaot

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Oleksandr Voytyuk

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Ioannis Dimitriou

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Fabrice Sircoulomb

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Arun Chandrakumar

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Marcel Deckert

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Andrew Scotter

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Shengqing Gu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Salima Janmohamed

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Feng Cong

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Paul D Simoncic

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Yasuyoshi Ueki

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Jose La Rose

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

language of work or name

English

0 references

publication date

1 December 2011

1 reference

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18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

147

1 reference

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18 January 2020

page(s)

1324-1339

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling

18 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

The macro domain is an ADP-ribose binding module

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Tyrosine kinase signalling in breast cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

The gene for cherubism maps to chromosome 4p16.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Cherubism--familial fibrous dysplasia of the jaws

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Tankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and capping

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Generation and characterization of telomere length maintenance in tankyrase 2-deficient mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Hypermetabolism, hyperphagia, and reduced adiposity in tankyrase-deficient mice

10 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

The 3BP2 adapter protein is required for optimal B-cell activation and thymus-independent type 2 humoral response

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

3BP2 deficiency impairs the response of B cells, but not T cells, to antigen receptor ligation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

The adapter 3BP2: how it plugs into leukocyte signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Regulation of FcepsilonRI-mediated degranulation by an adaptor protein 3BP2 in rat basophilic leukemia RBL-2H3 cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Mutations in the gene encoding c-Abl-binding protein SH3BP2 cause cherubism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Role of Src expression and activation in human cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475183

Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22153076

12 December 2020

inferred from PubMed ID database lookup

Identification of a novel mutation of SH3BP2 in cherubism and demonstration that SH3BP2 mutations lead to increased NFAT activation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22153076

12 December 2020

inferred from PubMed ID database lookup

[The adaptor protein 3BP2 in leukocyte signaling]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22153076

12 December 2020

inferred from PubMed ID database lookup

Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.10.045

7 January 2021

inferred from DOI database lookup

Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.10.045

7 January 2021

inferred from DOI database lookup

Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.10.045

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/J.CELL.2011.10.045

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22153076%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

2 references