FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the transcriptional regulation of FOXO1A (Q24300035)

positive regulation of transcription by RNA polymerase II

GOA release 2020-03-11

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GOA release 2020-03-11

5

Thomas J Hudson

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author name string

Fred B Berry

1

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Jonathan M Skarie

2

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Farideh Mirzayans

3

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Yannick Fortin

4

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Vincent Raymond

6

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Brian A Link

7

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Michael A Walter

Oxidative DNA damage in the human trabecular meshwork: clinical correlation in patients with primary open-angle glaucoma.

8

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language of work or name

English

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publication date

15 February 2008

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published in

Human Molecular Genetics

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volume

17

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issue

4

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page(s)

490-505

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cites work

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Oxidative stress affects cytoskeletal structure and cell-matrix interactions in cells from an ocular tissue: the trabecular meshwork

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Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro

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The forkhead/winged-helix gene, Mf1, is necessary for the normal development of the cornea and formation of the anterior chamber in the mouse eye

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Forkhead transcription factors: key players in development and metabolism

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The peroxisome and the eye

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Using zebrafish to study the complex genetics of glaucoma

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FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction

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Retinal oxidative stress induced by high intraocular pressure

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The role of oxidative stress in glaucoma

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Oxidative stress in glaucomatous neurodegeneration: mechanisms and consequences

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The mouse forkhead gene Foxc1 is required for primordial germ cell migration and antral follicle development

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Oxidative deoxyribonucleic acid damage in the eyes of glaucoma patients

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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The forkhead/winged helix gene Mf1 is disrupted in the pleiotropic mouse mutation congenital hydrocephalus

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Trabecular meshwork cellularity in primary open-angle glaucoma and nonglaucomatous normals

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Fox's in development and disease

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Reduced redox state allows prolonged survival of axotomized neonatal retinal ganglion cells

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Cell cycle and death control: long live Forkheads

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The forkhead transcription factor gene FKHL7 is responsible for glaucoma phenotypes which map to 6p25

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FOXC1 transcriptional regulation is mediated by N- and C-terminal activation domains and contains a phosphorylated transcriptional inhibitory domain

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Regulation of FOXC1 stability and transcriptional activity by an epidermal growth factor-activated mitogen-activated protein kinase signaling cascade

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