Subcellular Localization and Tumor-suppressive Functions of 15-Lipoxygenase 2 (15-LOX2) and Its Splice Variants (Q24300188)

https://api.crossref.org/works/10.1074/JBC.M301920200

Arachidonate 15-lipoxygenase type B

25 December 2023

main subject

1 reference

negative regulation of cell population proliferation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

https://api.crossref.org/works/10.1074/JBC.M301920200

25 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M301920200

25 December 2023

4

Dhyan Chandra

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12704195

25 December 2023

author name string

Bobby Bhatia

1

0 references

Shaohua Tang

3

0 references

Dharam Chopra

6

0 references

Peiying Yang

8

0 references

Carlos J. Maldonado

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12704195

25 December 2023

Russell D. Klein

5

1 reference

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25 December 2023

Scott B. Shappell

7

1 reference

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25 December 2023

Robert A. Newman

9

1 reference

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25 December 2023

Dean G. Tang

10

1 reference

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language of work or name

English

0 references

publication date

4 July 2003

0 references

18 April 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12704195

full work available at URL

25 December 2023

http://www.jbc.org/content/278/27/25091.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12704195

https://api.elsevier.com/content/article/PII:S0021925820869749?httpAccept=text/xml

25 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M301920200

https://api.elsevier.com/content/article/PII:S0021925820869749?httpAccept=text/plain

25 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M301920200

https://syndication.highwire.org/content/doi/10.1074/jbc.M301920200

25 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M301920200

Journal of Biological Chemistry

25 December 2023

published in

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volume

278

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issue

27

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page(s)

25091-100

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Differential characteristics of human 15-lipoxygenase isozymes and a novel splice variant of 15S-lipoxygenase

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15-lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma

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Alterations in lipoxygenase and cyclooxygenase-2 catalytic activity and mRNA expression in prostate carcinoma

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Differential growth factor responses of epithelial cell cultures derived from normal human prostate, benign prostatic hyperplasia, and primary prostate carcinoma

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The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum

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Identification of 12-lipoxygenase interaction with cellular proteins by yeast two-hybrid screening

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The N-terminal domain of the reticulocyte-type 15-lipoxygenase is not essential for enzymatic activity but contains determinants for membrane binding

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Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

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Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1.

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PPARgamma agonists inhibit cell growth and suppress the expression of cyclin D1 and EGF-like growth factors in ras-transformed rat intestinal epithelial cells

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5-Lipoxygenase compartmentalization in granulocytic cells is modulated by an internal bipartite nuclear localizing sequence and nuclear factor kappa B complex formation.

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Identification of a bipartite nuclear localization sequence necessary for nuclear import of 5-lipoxygenase

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Nuclear-localization-signal-dependent and nuclear-export-signal-dependent mechanisms determine the localization of 5-lipoxygenase

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Differential localization of 5- and 15-lipoxygenases to the nuclear envelope in RAW macrophages

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Determinants of 5-lipoxygenase nuclear localization using green fluorescent protein/5-lipoxygenase fusion proteins

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The N-terminal "beta-barrel" domain of 5-lipoxygenase is essential for nuclear membrane translocation

21 January 2018

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Structural and functional criteria reveal a new nuclear import sequence on the 5-lipoxygenase protein

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Identifiers

0 references