CNOT7/hCAF1 is involved in ICAM-1 and IL-8 regulation by tristetraprolin (Q24300970)

ZFP36 ring finger protein

GOA release 2020-03-11

1 reference

positive regulation of mRNA catabolic process

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Jia-Xin Shi

1

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Jia-Shu Li

2

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Rong Hu

3

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Yi Shi

4

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Xin Su

5

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Qin Li

6

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Feng Zhang

Tristetraprolin regulates interleukin-6, which is correlated with tumor progression in patients with head and neck squamous cell carcinoma

7

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language of work or name

English

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publication date

November 2014

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published in

Cellular Signalling

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volume

26

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issue

11

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page(s)

2390-6

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cites work

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Tristetraprolin down-regulates IL-23 expression in colon cancer cells

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Tristetraprolin down-regulates IL-17 through mRNA destabilization

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The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways?

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AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

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The BTG2 protein is a general activator of mRNA deadenylation

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Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover

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Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin

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MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitment

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MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding

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Tristetraprolin mediates interferon-gamma mRNA decay

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A role for Caf1 in mRNA deadenylation and decay in trypanosomes and human cells

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Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin

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The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex

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Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1

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Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.

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Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element

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MK2 posttranscriptionally regulates TNF-α-induced expression of ICAM-1 and IL-8 via tristetraprolin in human pulmonary microvascular endothelial cells

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