The phosphorylation of p25/TPPP by LIM kinase 1 inhibits its ability to assemble microtubules (Q24301086)

Tubulin polymerization promoting protein

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Karla Acevedo

1

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Mark E Graham

object named as

Mark E Graham

7

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Boris Sarcevic

object named as

Boris Sarcevic

5

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Phillip J. Robinson

object named as

Phillip J Robinson

8

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author name string

Rong Li

2

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Priscilla Soo

3

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Randy Suryadinata

4

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Valentina A Valova

6

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Ora Bernard

Experimental Cell Research

9

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language of work or name

English

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publication date

10 December 2007

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published in

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volume

313

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issue

20

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page(s)

4091-106

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cites work

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Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

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Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

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Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin

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LIM kinase 1 coordinates microtubule stability and actin polymerization in human endothelial cells

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A novel brain-specific 25 kDa protein (p25) is phosphorylated by a Ser/Thr-Pro kinase (TPK II) from tau protein kinase fractions

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A novel human gene whose product shares homology with bovine brain-specific protein p25 is expressed in fetal brain but not in adult brain

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Brain-specific p25 protein binds to tubulin and microtubules and induces aberrant microtubule assemblies at substoichiometric concentrations

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Dynamic targeting of microtubules by TPPP/p25 affects cell survival.

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TPPP/p25 promotes tubulin assemblies and blocks mitotic spindle formation

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Filamentous nerve cell inclusions in neurodegenerative diseases

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Alpha-synuclein and neurodegenerative diseases

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P25alpha immunoreactive but alpha-synuclein immunonegative neuronal inclusions in multiple system atrophy

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p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies

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Natively unfolded tubulin polymerization promoting protein TPPP/p25 is a common marker of alpha-synucleinopathies

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Rapid hybridoma screening method for the identification of monoclonal antibodies to low-abundance cytoplasmic proteins

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Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1

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Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin

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The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene

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LIM kinase 2 is widely expressed in all tissues

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Regulation of the ubiquitin-conjugating enzyme hHR6A by CDK-mediated phosphorylation

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Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L).

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Tissue expression and subcellular localization of the pro-survival molecule Bcl-w

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