Intracellular Ca2+ and the phospholipid PIP2 regulate the taste transduction ion channel TRPM5 (Q24301233)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14657398%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Intracellular Ca2+ and the phospholipid PIP2 regulate the taste transduction ion channel TRPM5 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14657398%20AND%20SRC:MED&resulttype=core&format=json

Cholinergic receptor muscarinic 1

21 December 2019

main subject

1 reference

positive regulation of ion transport

1 reference

Transient receptor potential cation channel, subfamily M, member 5

1 reference

Cholinergic receptor, muscarinic 1, CNS

1 reference

author

Emily R. Liman

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14657398%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

author name string

Dan Liu

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14657398%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

language of work or name

English

0 references

publication date

1 December 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14657398%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14657398%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

volume

100

1 reference

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21 December 2019

page(s)

15160-15165

1 reference

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21 December 2019

issue

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14657398%20AND%20SRC:MED&resulttype=core&format=json

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

21 December 2019

cites work

1 reference

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Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium

19 March 2017

1 reference

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Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

19 March 2017

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19 March 2017

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The capsaicin receptor: a heat-activated ion channel in the pain pathway

19 March 2017

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X-ray structure of a voltage-dependent K+ channel

19 March 2017

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Receptors and transduction in taste

19 March 2017

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Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways

19 March 2017

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19 March 2017

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The TRPM7 channel is inactivated by PIP(2) hydrolysis

19 March 2017

1 reference

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A TRP channel that senses cold stimuli and menthol

19 March 2017

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Molecular mechanisms of bitter and sweet taste transduction

19 March 2017

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LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability

19 March 2017

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TRP-PLIK, a bifunctional protein with kinase and ion channel activities

19 March 2017

1 reference

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Voltage dependence of the Ca2+-activated cation channel TRPM4

19 March 2017

1 reference

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TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization

19 March 2017

1 reference

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Identification of a cold receptor reveals a general role for TRP channels in thermosensation

19 March 2017

1 reference

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Loss of sex discrimination and male-male aggression in mice deficient for TRP2

19 March 2017

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Transduction of bitter and sweet taste by gustducin

19 March 2017

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A second subunit of the olfactory cyclic nucleotide-gated channel confers high sensitivity to cAMP

19 March 2017

1 reference

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TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i

19 March 2017

1 reference

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TRPV channels as temperature sensors

27 September 2017

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A transient receptor potential channel expressed in taste receptor cells

27 September 2017

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Visual transduction in Drosophila.

27 September 2017

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Immunocyte Ca2+ influx system mediated by LTRPC2.

27 September 2017

1 reference

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Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

27 September 2017

1 reference

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A Drosophila mechanosensory transduction channel

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299934

TRP2: a candidate transduction channel for mammalian pheromone sensory signaling.

27 September 2017

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Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools

27 September 2017

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OSM-9, a novel protein with structural similarity to channels, is required for olfaction, mechanosensation, and olfactory adaptation in Caenorhabditis elegans

27 September 2017

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Calcium-dependent inactivation of light-sensitive channels in Drosophila photoreceptors

27 September 2017

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Calcium-activated non-specific cation channels

27 September 2017

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Localization of phosphatidylinositol signaling components in rat taste cells: role in bitter taste transduction

27 September 2017

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Identification of a Drosophila gene encoding a calmodulin-binding protein with homology to the trp phototransduction gene

27 September 2017

1 reference

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TRPM5 is a voltage-modulated and Ca(2+)-activated monovalent selective cation channel.

27 September 2017

1 reference

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Mtr1, a novel biallelically expressed gene in the center of the mouse distal chromosome 7 imprinting cluster, is a member of the Trp gene family

30 May 2018

1 reference

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Vesicle pools and Ca2+ microdomains: new tools for understanding their roles in neurotransmitter release

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299934

A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299934

PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299934

Regulation by voltage and adenine nucleotides of a Ca2+-activated cation channel from hamster vomeronasal sensory neurons

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299934

Multiple regulatory sites in large-conductance calcium-activated potassium channels.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299934

Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299934

Taste receptor cell responses to the bitter stimulus denatonium involve Ca2+ influx via store-operated channels.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299934

A unified nomenclature for the superfamily of TRP cation channels.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299934

Calcium influx via TRP channels is required to maintain PIP2 levels in Drosophila photoreceptors.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299934

Mechanism of calcium gating in small-conductance calcium-activated potassium channels.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299934

A bitter substance induces a rise in intracellular calcium in a subpopulation of rat taste cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299934

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

29 November 2018

1 reference

12 December 2020

Changes in IP3 and cytosolic Ca2+ in response to sugars and non-sugar sweeteners in transduction of sweet taste in the rat

1 reference

12 December 2020

Bitter taste transduction of denatonium in the mudpuppy Necturus maculosus

1 reference

12 December 2020

Incorporation of Galpha(z)-specific sequence at the carboxyl terminus increases the promiscuity of galpha(16) toward G(i)-coupled receptors

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.2334159100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14657398%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14657398%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference