Expression of ATP binding cassette-transporter ABCG1 prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol (Q24301664)

ABC-type sterol transporter activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Thomas Engel

1

Thomas

Engel

1 reference

20 April 2024

Frank Kannenberg

2

Frank

Kannenberg

1 reference

20 April 2024

Manfred Fobker

3

Manfred

Fobker

1 reference

20 April 2024

Jerzy-Roch Nofer

4

Jerzy-Roch

Nofer

1 reference

20 April 2024

Guenther Bode

5

Guenther

Bode

1 reference

20 April 2024

Aloys Lueken

6

Aloys

Lueken

1 reference

20 April 2024

Gerd Assmann

7

Gerd

Assmann

1 reference

20 April 2024

Udo Seedorf

8

Udo

Oxysterols: friends, foes, or just fellow passengers?

Seedorf

1 reference

20 April 2024

language of work or name

English

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publication date

17 April 2007

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published in

FEBS Letters

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volume

581

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issue

8

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page(s)

1673-80

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cites work

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Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects

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Expression and functional characterization of ABCG1 splice variant ABCG1(666)

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Ablation of the cholesterol transporter adenosine triphosphate-binding cassette transporter G1 reduces adipose cell size and protects against diet-induced obesity.

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Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.

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Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system

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The small heterodimer partner interacts with the liver X receptor alpha and represses its transcriptional activity

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The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages

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Glycolysis in P-glycoprotein-overexpressing human tumor cell lines. Effects of resistance-modifying agents

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Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization

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Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages

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Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.

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Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1

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ABCA1 mediates high-affinity uptake of 25-hydroxycholesterol by membrane vesicles and rapid efflux of oxysterol by intact cells

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Esterification of oxysterols by human plasma lecithin-cholesterol acyltransferase

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Structures of Biologically Active Oxysterols Determine Their Differential Effects on Phospholipid Membranes†

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Measuring cholesterol in macrophages: comparison of high-performance liquid chromatography and gas-liquid chromatography with enzymatic fluorometry

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7 January 2021

Mitochondrial perturbation, oxidative stress and lysosomal destabilization are involved in 7beta-hydroxysitosterol and 7beta-hydroxycholesterol triggered apoptosis in human colon cancer cells

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Oxysterols and atherosclerosis

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Metabolism of 7β-Hydroxycholesterol-4-14C in rat

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Induction by verapamil of a rapid increase in ATP consumption in multidrug‐resistant tumor cells

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Oxysterols: modulators of cholesterol metabolism and other processes

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Bcl-2 down-regulation and tubulin subtype composition are involved in resistance of ovarian cancer cells to vinflunine

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Impaired development of atherosclerosis in hyperlipidemic Ldlr-/- and ApoE-/- mice transplanted with Abcg1-/- bone marrow

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Total body ABCG1 expression protects against early atherosclerotic lesion development in mice

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