Nucleocytoplasmic shuttling of dysbindin-1, a schizophrenia-related protein, regulates synapsin I expression (Q24301877)

GOA release 2020-03-11

Exportin 1

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GOA release 2020-03-11

Erkang Fei

1

Erkang

Fei

1 reference

20 October 2023

Xiaochuan Ma

2

Xiaochuan

Ma

1 reference

20 October 2023

Cuiqing Zhu

3

Cuiqing

Zhu

1 reference

20 October 2023

Ting Xue

4

Ting

Xue

1 reference

20 October 2023

Jie Yan

5

Jie

Yan

1 reference

20 October 2023

Yuxia Xu

6

Yuxia

Xu

1 reference

20 October 2023

Jiangning Zhou

7

Jiangning

Zhou

1 reference

20 October 2023

Guanghui Wang

8

Guanghui

Wang

1 reference

Journal of Biological Chemistry

20 October 2023

language of work or name

English

0 references

publication date

3 December 2010

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published in

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volume

285

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issue

49

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page(s)

38630-40

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cites work

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Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin

19 March 2017

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Reinvestigation of the dysbindin subunit of BLOC-1 (biogenesis of lysosome-related organelles complex-1) as a dystrobrevin-binding protein

19 March 2017

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Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1)

19 March 2017

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Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1)

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Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia

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Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia

19 March 2017

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CRM1-mediated recycling of snurportin 1 to the cytoplasm

19 March 2017

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19 March 2017

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Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain

19 March 2017

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Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex

19 March 2017

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Disruption of two novel genes by a translocation co-segregating with schizophrenia

19 March 2017

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Role of dysbindin in dopamine receptor trafficking and cortical GABA function

19 March 2017

1 reference

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Impaired long-term memory retention and working memory in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release

19 March 2017

1 reference

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Evidence that the BLOC-1 protein dysbindin modulates dopamine D2 receptor internalization and signaling but not D1 internalization

19 March 2017

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Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia

19 March 2017

1 reference

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Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice

19 March 2017

1 reference

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Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

19 March 2017

1 reference

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Dysbindin regulates the transcriptional level of myristoylated alanine-rich protein kinase C substrate via the interaction with NF-YB in mice brain

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Dysbindin regulates hippocampal LTP by controlling NMDA receptor surface expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Association study of DTNBP1 with schizophrenia in a US sample

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Neurobehavioral abnormalities in the dysbindin-1 mutant, sandy, on a C57BL/6J genetic background

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Dysbindin-1, a schizophrenia-related protein, functionally interacts with the DNA- dependent protein kinase complex in an isoform-dependent manner

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Disorders of lysosome-related organelle biogenesis: clinical and molecular genetics

27 September 2017

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Cis- and trans- loci influence expression of the schizophrenia susceptibility gene DTNBP1.

27 September 2017

1 reference

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Crossing the nuclear envelope: hierarchical regulation of nucleocytoplasmic transport

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

DTNBP1 (Dystrobrevin binding protein 1) and schizophrenia: association evidence in the 3' end of the gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Hyperactivation of midbrain dopaminergic system in schizophrenia could be attributed to the down-regulation of dysbindin.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Nucleocytoplasmic shuttling of receptor-interacting protein 3 (RIP3): identification of novel nuclear export and import signals in RIP3.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Dysbindin-1 and schizophrenia: from genetics to neuropathology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad families

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Nuclear export signal located within theDNA-binding domain of the STAT1transcription factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Synapsins as regulators of neurotransmitter release

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Synaptic vesicle recycling in synapsin I knock-out mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Synapsin I, synapsin II, and synaptophysin: marker proteins of synaptic vesicles

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

The synapsins and the regulation of synaptic function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Dysbindin modulates prefrontal cortical glutamatergic circuits and working memory function in mice.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Association study of neuregulin 1 gene with schizophrenia.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Altered synaptophysin expression as a marker of synaptic pathology in schizophrenia

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Identification of a high-risk haplotype for the dystrobrevin binding protein 1 (DTNBP1) gene in the Irish study of high-density schizophrenia families

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Association study of dysbindin gene with clinical and outcome measures in a representative cohort of Italian schizophrenic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Dysbindin gene (DTNBP1) and schizophrenia in Korean population

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Mixture model clustering of phenotype features reveals evidence for association of DTNBP1 to a specific subtype of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Reduced DTNBP1 (dysbindin-1) mRNA in the hippocampal formation of schizophrenia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Behavioral abnormalities and dopamine reductions in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Dysbindin deficiency in sandy mice causes reduction of snapin and displays behaviors related to schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Behavioral characterization of dysbindin-1 deficient sandy mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Schizophrenia: the "BLOC" may be in the endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

SNAP-25 deficit and hippocampal connectivity in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Reduction of synapsin III in the prefrontal cortex of individuals with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Synapsin-I- and synapsin-II-null mice display an increased age-dependent cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Flies lacking all synapsins are unexpectedly healthy but are impaired in complex behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Two sites of action for synapsin domain E in regulating neurotransmitter release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107912

Association study of NRG1, DTNBP1, RGS4, G72/G30, and PIP5K2A with schizophrenia and symptom severity in a Hungarian sample

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Cis-acting variation in the expression of a high proportion of genes in human brain

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992295

Family-based association study of DTNBP1 in 6p22.3 and schizophrenia

29 November 2018

1 reference

12 December 2020

Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics

1 reference

12 December 2020

Preferential transmission of the high activity allele of COMT in schizophrenia

1 reference

12 December 2020

Relationship between a high-risk haplotype in the DTNBP1 (dysbindin) gene and clinical features of schizophrenia

1 reference

12 December 2020

Neurobiology of schizophrenia

1 reference

12 December 2020

release_wwcbx4mrlbd55pp5eeb6vsy2bq

Identifiers

DOI

10.1074/JBC.M110.107912

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Fatcat ID

0 references

PMC publication ID

2992295

0 references