The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1 (Q24302164)

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Alexander V Loktev

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Emmy W Verschuren

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Julie D R Reimann

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Peter K Jackson

Polo-like kinase-2 is required for centriole duplication in mammalian cells

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language of work or name

English

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publication date

27 January 2006

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published in

Cell

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volume

124

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issue

2

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page(s)

367-80

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cites work

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7 January 2021

EVI5 is a novel centrosomal protein that binds to alpha- and gamma-tubulin

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Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex

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Recycling the Cell Cycle

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Centrosomes have a role in regulating the destruction of cyclin B in early Drosophila embryos.

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The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

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Aggresomes, inclusion bodies and protein aggregation

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Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

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Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

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Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A.

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Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex

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E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

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Proviral integrations at the Evi5 locus disrupt a novel 90 kDa protein with homology to the Tre2 oncogene and cell-cycle regulatory proteins

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The many faces of beta-TrCP E3 ubiquitin ligases: reflections in the magic mirror of cancer

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Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome

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Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells

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Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate.

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Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function

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Identification of genes periodically expressed in the human cell cycle and their expression in tumors

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Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1

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Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome

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Mitotic regulation of the human anaphase-promoting complex by phosphorylation

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NB4S, a member of the TBC1 domain family of genes, is truncated as a result of a constitutional t(1;10)(p22;q21) chromosome translocation in a patient with stage 4S neuroblastoma

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7 January 2021

The anaphase-promoting complex: it's not just for mitosis any more.

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7 January 2021

Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle

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7 January 2021

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

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7 January 2021

Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins

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7 January 2021

Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates

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Role of Plk2 (Snk) in mouse development and cell proliferation

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The Spindle Assembly and Spindle Position Checkpoints

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7 January 2021