Phosphoinositide 3-kinase delta (PI3Kδ) in leukocyte signaling and function (Q24302466)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940048%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Phosphoinositide 3-kinase delta (PI3Kδ) in leukocyte signaling and function (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940048%20AND%20SRC:MED&resulttype=core&format=json

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

15 February 2020

main subject

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GOA release 2020-03-11

neutrophil extravasation

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GOA release 2020-03-11

author

Wai-Ping Fung-Leung

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940048%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

author name string

Wai-Ping Fung-Leung

series ordinal

1

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language of work or name

English

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publication date

16 October 2010

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940048%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

number of pages

6

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inferred from page(s)

published in

Cellular Signalling

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940048%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

volume

23

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940048%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

issue

4

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15 February 2020

page(s)

603-608

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940048%20AND%20SRC:MED&resulttype=core&format=json

Role of PI3Kdelta and PI3Kgamma in inflammatory arthritis and tissue localization of neutrophils

15 February 2020

cites work

1 reference

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7 January 2021

Targeting phosphoinositide 3-kinase: moving towards therapy

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7 January 2021

Discovery of dual inhibitors of the immune cell PI3Ks p110delta and p110gamma: a prototype for new anti-inflammatory drugs

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7 January 2021

p110γ and p110δ Phosphoinositide 3-Kinase Signaling Pathways Synergize to Control Development and Functions of Murine NK Cells

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7 January 2021

The multiple roles of phosphoinositide 3-kinase in mast cell biology

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7 January 2021

Phosphoinositide 3-kinase-delta inhibitor reduces vascular permeability in a murine model of asthma.

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7 January 2021

Genetic or pharmaceutical blockade of p110delta phosphoinositide 3-kinase enhances IgE production

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7 January 2021

Role of phosphoinositide 3-kinase p110 delta in TLR4- and TLR9-mediated B cell cytokine production and differentiation.

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7 January 2021

Selective role of PI3K delta in neutrophil inflammatory responses

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7 January 2021

Therapeutic potential of phosphoinositide 3-kinase inhibitors.

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7 January 2021

Essential role for the p110delta phosphoinositide 3-kinase in the allergic response

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7 January 2021

The p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitors

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7 January 2021

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

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7 January 2021

The emerging mechanisms of isoform-specific PI3K signalling

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7 January 2021

p110gamma and p110delta isoforms of phosphoinositide 3-kinase differentially regulate natural killer cell migration in health and disease

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7 January 2021

Phosphoinositide 3-kinases gamma and delta, linkers of coordinate C5a receptor-Fcgamma receptor activation and immune complex-induced inflammation

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7 January 2021

A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2010.10.002

7 January 2021

The p110 delta of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2010.10.002

7 January 2021

Inhibition of phosphoinositide 3-kinase delta attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model

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7 January 2021

Aerosolized phosphoinositide 3-kinase gamma/delta inhibitor TG100-115 [3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol] as a therapeutic candidate for asthma and chronic obstructive pulmonary disease

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7 January 2021

Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex.

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7 January 2021

Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice

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7 January 2021

Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2010.10.002

7 January 2021

Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2010.10.002

7 January 2021

Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110delta function in B cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2010.10.002

7 January 2021

Leukocyte PI3K and PI3K have temporally distinct roles for leukocyte recruitment in vivo

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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2010.10.002

7 January 2021

The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion

1 reference

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7 January 2021

Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2010.10.002

7 January 2021

CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2010.10.002

7 January 2021

PI3K p110delta regulates T-cell cytokine production during primary and secondary immune responses in mice and humans

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7 January 2021

Phosphatidylinositol 3-kinase-δ inhibitor CAL-101 shows promising preclinical activity in chronic lymphocytic leukemia by antagonizing intrinsic and extrinsic cellular survival signals

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2010.10.002

7 January 2021

Phosphoinositide 3-kinase p110 delta regulates natural antibody production, marginal zone and B-1 B cell function, and autoantibody responses

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2010.10.002

7 January 2021

The p110 delta isoform of phosphatidylinositol 3-kinase controls the quality of secondary anti-Leishmania immunity by regulating expansion and effector function of memory T cell subsets

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2010.10.002

7 January 2021

Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement

1 reference

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7 January 2021

Cutting edge: differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemotaxis and homing

1 reference

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7 January 2021

Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.

1 reference

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7 January 2021

Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4+CD25+Foxp3+ regulatory T cells

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7 January 2021

The p110delta isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells

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7 January 2021

Requirement for phosphoinositide 3-kinase p110delta signaling in B cell antigen receptor-mediated antigen presentation

1 reference

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7 January 2021

Tissue- and stimulus-dependent role of phosphatidylinositol 3-kinase isoforms for neutrophil recruitment induced by chemoattractants in vivo

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7 January 2021

Isoform-specific functions of phosphoinositide 3-kinases: p110 delta but not p110 gamma promotes optimal allergic responses in vivo

1 reference

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7 January 2021

10.1016/J.CELLSIG.2010.10.002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20940048%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference