Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice (Q24306510)

2

Masakazu

Akahori

1 reference

19 October 2023

Minoru Obazawa

3

Minoru

Obazawa

1 reference

19 October 2023

Masayoshi Minami

4

Masayoshi

Minami

1 reference

19 October 2023

Toru Noda

5

Toru

Noda

1 reference

19 October 2023

Naoki Nakaya

6

Naoki

Nakaya

1 reference

19 October 2023

Stanislav Tomarev

7

Stanislav

Tomarev

1 reference

19 October 2023

Kazuhide Kawase

8

Kazuhide

Kawase

1 reference

19 October 2023

Tetsuya Yamamoto

9

Tetsuya

Yamamoto

1 reference

19 October 2023

Setsuko Noda

10

Setsuko

Noda

1 reference

19 October 2023

Masaki Sasaoka

11

Masaki

Sasaoka

1 reference

19 October 2023

Atsushi Shimazaki

12

Atsushi

Shimazaki

1 reference

19 October 2023

Yuichiro Takada

13

Yuichiro

Takada

1 reference

19 October 2023

Takeshi Iwata

14

Takeshi

A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

Iwata

1 reference

19 October 2023

language of work or name

English

0 references

publication date

1 July 2010

0 references

published in

Human Molecular Genetics

0 references

volume

19

0 references

issue

13

0 references

page(s)

2606-15

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

The number of people with glaucoma worldwide in 2010 and 2020

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Functional proteomics mapping of a human signaling pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Identification of a transcription factor IIIA-interacting protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Identification of three different truncating mutations in cytochrome P4501B1 (CYP1B1) as the principal cause of primary congenital glaucoma (Buphthalmos) in families linked to the GLC3A locus on chromosome 2p21

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Rab proteins as membrane organizers

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Evaluation of optineurin sequence variations in 1,048 patients with open-angle glaucoma

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Different optineurin mutation pattern in primary open-angle glaucoma

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Adult-onset primary open-angle glaucoma caused by mutations in optineurin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Huntingtin interacts with a family of WW domain proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Transgenic mice expressing the Tyr437His mutant of human myocilin protein develop glaucoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Studies of optineurin, a glaucoma gene: Golgi fragmentation and cell death from overexpression of wild-type and mutant optineurin in two ocular cell types

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Optineurin increases cell survival and translocates to the nucleus in a Rab8-dependent manner upon an apoptotic stimulus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Cell-free cotranslation and selection using in vitro virus for high-throughput analysis of protein-protein interactions and complexes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Identification of a novel adult-onset primary open-angle glaucoma (POAG) gene on 5q22.1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

The definition and classification of glaucoma in prevalence surveys

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Mutant rab8 Impairs docking and fusion of rhodopsin-bearing post-Golgi membranes and causes cell death of transgenic Xenopus rods

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Identification of a gene that causes primary open angle glaucoma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Number of people with glaucoma worldwide

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Molecular genetic analysis of optineurin gene for primary open-angle and normal tension glaucoma in the Japanese population

27 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ146

Distribution of optineurin sequence variations in an ethnically diverse population of low-tension glaucoma patients from the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ146

The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ146

Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ146

Expression of mutated mouse myocilin induces open-angle glaucoma in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ146

The Rab8 GTPase regulates apical protein localization in intestinal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ146

Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ146

A Glaucoma-Associated Mutant of Optineurin Selectively Induces Death of Retinal Ganglion Cells Which Is Inhibited by Antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ146

[Polymorphisms of myocilin and optineurin in primary open angle glaucoma patients].

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Prevalence of myocilin and optineurin sequence variants in German normal tension glaucoma patients.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883340

Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20388642

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Clinical features and course of patients with glaucoma with the E50K mutation in the optineurin gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20388642

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDQ146

1 reference

release_g6iheapd3nggzozhl47kxryity

3393084

Fatcat ID

0 references

3393084

1 reference

1 reference

1 reference