Copine-I represses NF-kappaB transcription by endoproteolysis of p65 (Q24307551)

GOA release 2020-03-11

Copine 1

1 reference

negative regulation of NIK/NF-kappaB signaling

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

C S Ramsey

1

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F Yeung

2

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P B Stoddard

3

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D Li

4

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C E Creutz

5

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M W Mayo

The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression

6

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language of work or name

English

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publication date

5 June 2008

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published in

Oncogene

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volume

27

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issue

25

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page(s)

3516-26

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cites work

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Duration of nuclear NF-kappaB action regulated by reversible acetylation

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NF-kappaB RelA phosphorylation regulates RelA acetylation

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A novel DNA-binding motif shares structural homology to DNA replication and repair nucleases and polymerases

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The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans

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Ligand recognition by the I domain-containing integrins

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Structure of an IkappaBalpha/NF-kappaB complex

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase

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Copines: a ubiquitous family of Ca(2+)-dependent phospholipid-binding proteins

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Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

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The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

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NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

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Caspase-3-mediated cleavage of the NF-kappa B subunit p65 at the NH2 terminus potentiates naphthoquinone analog-induced apoptosis

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A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit

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PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit

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Mechanism of kappa B DNA binding by Rel/NF-kappa B dimers

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Novel effects of neutrophil-derived proteinase 3 and elastase on the vascular endothelium involve in vivo cleavage of NF-kappaB and proapoptotic changes in JNK, ERK, and p38 MAPK signaling pathways

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Functional characterization of the NF-kappa B p65 transcriptional activator and an alternatively spliced derivative

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Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response

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Biochemical characterization of copine: a ubiquitous Ca2+-dependent, phospholipid-binding protein

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Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues

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A novel DNA recognition mode by the NF-kappa B p65 homodimer

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inferred from DOI database lookup

7 January 2021

based on heuristic

The C2 domain calcium-binding motif: structural and functional diversity

1 reference

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