G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase (Q24307705)

Potassium inwardly rectifying channel subfamily J member 5

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Dopamine receptor D4

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Potassium inwardly rectifying channel subfamily J member 3

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inward rectifier potassium channel activity

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Adrenergic receptor, beta 2

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Michel Bouvier

8

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author name string

Natalie Lavine

1

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Nathalie Ethier

2

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James N Oak

3

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Lin Pei

4

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Fang Liu

5

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Phan Trieu

6

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R Victor Rebois

7

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Terence E Hebert

9

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Hubert H M Van Tol

Journal of Biological Chemistry

10

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language of work or name

English

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publication date

29 November 2002

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published in

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volume

277

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issue

48

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page(s)

46010-9

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cites work

Stable association of G proteins with beta 2AR is independent of the state of receptor activation.

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The GppNHp-activated adenylyl cyclase complex from turkey erythrocyte membranes can be isolated with its beta gamma subunits

21 January 2018

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Does subunit dissociation necessarily accompany the activation of all heterotrimeric G proteins?

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Rethinking receptor-G protein-effector interactions

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A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2

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The cardiac inward rectifier K+ channel subunit, CIR, does not comprise the ATP-sensitive K+ channel, IKATP.

21 January 2018

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A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels

21 January 2018

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A trafficking checkpoint controls GABA(B) receptor heterodimerization

21 January 2018

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Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart

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Isolation of 2000-kDa complexes of N-methyl-D-aspartate receptor and postsynaptic density 95 from mouse brain

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Proteomic analysis of NMDA receptor-adhesion protein signaling complexes

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A G protein-gated K channel is activated via beta 2-adrenergic receptors and G beta gamma subunits in Xenopus oocytes

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Gbetagamma subunit combinations differentially modulate receptor and effector coupling in vivo

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Overexpression of beta 1 and beta 2 adrenergic receptors in rat atrial myocytes. Differential coupling to G protein-gated inward rectifier K(+) channels via G(s) and G(i)/o.

21 January 2018

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SH3 binding domains in the dopamine D4 receptor

21 January 2018

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Co-expression of human Kir3 subunits can yield channels with different functional properties

21 January 2018

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Antagonists of the receptor-G protein interface block Gi-coupled signal transduction.

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Molecular cloning and characterization of a Ca2+/calmodulin-insensitive adenylyl cyclase from rat brain

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GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels

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Specific regions of heteromeric subunits involved in enhancement of G protein-gated K+ channel activity

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Recombinant G-protein beta gamma-subunits activate the muscarinic-gated atrial potassium channel

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Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells

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Vesicle budding on Golgi membranes: regulation by G proteins and myosin motors

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Regulation of the golgi structure by the alpha subunits of heterotrimeric G proteins

21 January 2018

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A putative heterotrimeric G protein inhibits the fusion of COPI-coated vesicles. Segregation of heterotrimeric G proteins from COPI-coated vesicles

21 January 2018

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Gbetagamma-mediated regulation of Golgi organization is through the direct activation of protein kinase D

21 January 2018

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Assembly and intracellular targeting of the betagamma subunits of heterotrimeric G proteins

21 January 2018

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The A-kinase anchor protein MAP2B and cAMP-dependent protein kinase are associated with class C L-type calcium channels in neurons

21 January 2018

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Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79.

21 January 2018

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Signaling complexes: biophysical constraints on intracellular communication

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GTP binding to Gs does not promote subunit dissociation

21 January 2018

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7 January 2021

Evidence for stimulation of adenylyl cyclase by an activated G(s) heterotrimer in cell membranes: an experimental method for controlling the G(s) subunit composition of cell membranes

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7 January 2021

Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)

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7 January 2021

Visualization of agonist-induced sequestration and down-regulation of a green fluorescent protein-tagged beta2-adrenergic receptor

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7 January 2021

Internal trafficking and surface mobility of a functionally intact beta2-adrenergic receptor-green fluorescent protein conjugate

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7 January 2021

Cardiac muscarinic potassium channel activity is attenuated by inhibitors of G beta gamma

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7 January 2021

Characterization of G-protein-gated K+ channels composed of Kir3.2 subunits in dopaminergic neurons of the substantia nigra.

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7 January 2021