Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein (Q24308811)

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English	Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein	scientific article

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scholarly article

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15 October 2019

Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein (English)

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15 October 2019

Zinc finger and BTB domain containing 16

1 reference

GOA release 2020-03-11

protein homodimerization activity

1 reference

GOA release 2020-03-11

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based on heuristic

inferred from title

protein-protein interaction

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based on heuristic

inferred from title

5

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15 October 2019

Christine Chomienne

10

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15 October 2019

author name string

S Dong

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15 October 2019

J Zhu

2

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15 October 2019

A Reid

3

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15 October 2019

P Strutt

4

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15 October 2019

H J Zhong

6

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15 October 2019

Z Y Wang

7

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15 October 2019

J Licht

8

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15 October 2019

Z Chen

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15 October 2019

A Zelent

12

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15 October 2019

S J Chen

13

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15 October 2019

S Waxman

9

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15 October 2019

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publication date

1 April 1996

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15 October 2019

Proceedings of the National Academy of Sciences of the United States of America

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15 October 2019

93

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15 October 2019

8

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15 October 2019

3624-3629

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15 October 2019

The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB

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19 March 2017

Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia

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19 March 2017

Fusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia

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19 March 2017

PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors

1 reference

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19 March 2017

Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system

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19 March 2017

Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins

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19 March 2017

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

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19 March 2017

The POZ domain: a conserved protein-protein interaction motif

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19 March 2017

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

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19 March 2017

Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma

1 reference

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19 March 2017

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

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19 March 2017

Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39661

19 March 2017

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

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19 March 2017

Nuclear receptor that identifies a novel retinoic acid response pathway

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19 March 2017

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

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19 March 2017

Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39661

7 April 2017

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

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7 April 2017

Firefly luciferase gene: structure and expression in mammalian cells

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7 April 2017

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR

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27 September 2017

The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion

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27 September 2017

Translocation of the RAR alpha locus to the PML or PLZF gene in acute promyelocytic leukaemia

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27 September 2017

Expression of the zinc-finger gene PLZF at rhombomere boundaries in the vertebrate hindbrain

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27 September 2017

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27 September 2017

Effect of retinoic acid isomers on proliferation, differentiation and PML relocalization in the APL cell line NB4.

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27 September 2017

Breakpoint clusters of the PML gene in acute promyelocytic leukemia: primary structure of the reciprocal products of the PML-RARA gene in a patient with t(15;17).

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30 May 2018

Characterization of the PML-RAR alpha chimeric product of the acute promyelocytic leukemia-specific t(15;17) translocation

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30 May 2018

Formation of nucleophosmin/B23 oligomers requires both the amino- and the carboxyl-terminal domains of the protein.

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30 May 2018

Reduced and altered DNA-binding and transcriptional properties of the PLZF-retinoic acid receptor-alpha chimera generated in t(11;17)-associated acute promyelocytic leukemia.

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29 November 2018

Molecular rearrangements of the MYL gene in acute promyelocytic leukemia (APL, M3) define a breakpoint cluster region as well as some molecular variants

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rearrangements in the second intron of the RARA gene are present in a large majority of patients with acute promyelocytic leukemia and are used as molecular marker for retinoic acid-induced leukemic cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8622986

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute promyelocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/8622986

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.93.8.3624

1 reference

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15 October 2019

1996PNAS...93.3624D

0 references

1 reference

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15 October 2019

1 reference

Europe PubMed Central

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15 October 2019

ResearchGate publication ID

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