LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia (Q24309133)

negative regulation of apoptotic process in bone marrow cell

GO:0071865

2 references

GO:0071866

apoptotic process in bone marrow cell

GOA release 2020-03-11

1 reference

regulation of cell proliferation in bone marrow

GO:0071839

1 reference

cell proliferation in bone marrow

GO:0071863

1 reference

positive regulation of cell proliferation in bone marrow

GO:0071838

1 reference

Lymphoid enhancer binding factor 1

GO:0071864

1 reference

GOA release 2020-03-11

4

Axel Schambach

0 references

Martin Stanulla

12

object named as

Martin Stanulla

0 references

author name string

Julia Skokowa

1

0 references

Gunnar Cario

2

0 references

Murat Uenalan

3

0 references

Manuela Germeshausen

5

0 references

Karin Battmer

6

0 references

Cornelia Zeidler

7

0 references

Ulrich Lehmann

8

0 references

Matthias Eder

9

0 references

Christopher Baum

10

0 references

Rudolf Grosschedl

11

0 references

Michaela Scherr

13

0 references

Karl Welte

Severe congenital neutropenia

14

0 references

language of work or name

English

0 references

publication date

October 2006

0 references

published in

Nature Medicine

0 references

volume

12

0 references

issue

10

0 references

page(s)

1191-7

0 references

cites work

1 reference

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

1 reference

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

Survivin and molecular pathogenesis of colorectal cancer.

21 January 2018

1 reference

CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors

21 January 2018

1 reference

Induction of granulocytic differentiation by 2 pathways

21 January 2018

1 reference

The incidence of leukemia and mortality from sepsis in patients with severe congenital neutropenia receiving long-term G-CSF therapy

21 January 2018

1 reference

Heterogeneous expression pattern of pro- and anti-apoptotic factors in myeloid progenitor cells of patients with severe congenital neutropenia treated with granulocyte colony-stimulating factor.

21 January 2018

1 reference

Mutations in the gene for the granulocyte colony-stimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia

21 January 2018

1 reference

Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2

21 January 2018

1 reference

Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia

21 January 2018

1 reference

WNT signaling and lymphocyte development

21 January 2018

1 reference

TGFbeta3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development

21 January 2018

1 reference

The notch intracellular domain can function as a coactivator for LEF-1

21 January 2018

1 reference

Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin.

21 January 2018

1 reference

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions

21 January 2018

1 reference

LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

21 January 2018

1 reference

Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin

21 January 2018

1 reference

Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism

21 January 2018

1 reference

Wnt-3A/beta-catenin signaling induces transcription from the LEF-1 promoter

21 January 2018

1 reference

Autoregulation of the human C/EBP alpha gene by stimulation of upstream stimulatory factor binding

21 January 2018

1 reference

C/EBPalpha determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiation

21 January 2018

1 reference

Phosphorylation of C/EBPalpha inhibits granulopoiesis

21 January 2018

1 reference

Induction of C/EBPalpha activity alters gene expression and differentiation of human CD34+ cells.

21 January 2018

1 reference

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice

21 January 2018

1 reference

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

21 January 2018

1 reference

Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations.

21 January 2018

1 reference

CCAAT/enhancer-binding protein-alpha cooperates with p21 to inhibit cyclin-dependent kinase-2 activity and induces growth arrest independent of DNA binding

21 January 2018

1 reference

c-Myc is a critical target for c/EBPalpha in granulopoiesis.

21 January 2018

1 reference

Lymphoid enhancer factor/T cell factor expression in colorectal cancer

21 January 2018

1 reference

Distinct roles for Xenopus Tcf/Lef genes in mediating specific responses to Wnt/beta-catenin signalling in mesoderm development.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/NM1474

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1018919185

0 references

Fatcat ID

release_2qmxtwghtffuhadzlhjn5qyzpa

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2qmxtwghtffuhadzlhjn5qyzpa

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

17063141

1 reference

Consolidated OpenCitations Corpus – April 2017