Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice (Q24309428)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18596921%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice (English)

1 reference

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Fibroblast growth factor 8

9 January 2020

main subject

1 reference

GOA release 2020-03-11

bone development

1 reference

GOA release 2020-03-11

author

Wilson Chung

2

1 reference

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9 January 2020

Andrew A Dwyer

10

1 reference

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9 January 2020

Simon Pearce

16

1 reference

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9 January 2020

Moosa Mohammadi

19

1 reference

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9 January 2020

21

Nelly Pitteloud

1 reference

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9 January 2020

5

Lacey Plummer

1 reference

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9 January 2020

Janet E. Hall

1 reference

ORCID Public Data File 2021

Richard Quinton

11

object named as

Richard Quinton

1 reference

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9 January 2020

1

John Falardeau

1 reference

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9 January 2020

3

Andrew Beenken

1 reference

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9 January 2020

4

Taneli Raivio

1 reference

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9 January 2020

6

Yisrael Sidis

1 reference

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9 January 2020

Elka Jacobson-Dickman

7

object named as

Elka E Jacobson-Dickman

1 reference

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9 January 2020

8

Anna V Eliseenkova

1 reference

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9 January 2020

13

Janet E Hall

1 reference

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9 January 2020

14

Celine Huot

1 reference

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9 January 2020

author name string

Jinghong Ma

9

1 reference

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9 January 2020

Sandra Na

12

1 reference

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9 January 2020

Natalie Alois

15

1 reference

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9 January 2020

Lindsay W Cole

17

1 reference

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9 January 2020

Virginia Hughes

18

1 reference

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9 January 2020

Pei Tsai

20

1 reference

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9 January 2020

language of work or name

English

0 references

publication date

1 August 2008

1 reference

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Journal of Clinical Investigation

9 January 2020

published in

1 reference

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9 January 2020

volume

118

1 reference

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9 January 2020

page(s)

2822-2831

1 reference

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9 January 2020

issue

8

1 reference

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Impaired FGF signaling contributes to cleft lip and palate

9 January 2020

cites work

1 reference

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Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism

19 March 2017

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Kallmann syndrome: mutations in the genes encoding prokineticin-2 and prokineticin receptor-2

19 March 2017

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Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family

19 March 2017

1 reference

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Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain

19 March 2017

1 reference

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Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

19 March 2017

1 reference

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The GPR54 gene as a regulator of puberty

19 March 2017

1 reference

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Molecular regionalization of the neocortex is disrupted in Fgf8 hypomorphic mutants

19 March 2017

1 reference

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Neocortex patterning by the secreted signaling molecule FGF8

19 March 2017

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Genetics of Hirschsprung disease

19 March 2017

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Genomic structure, sequence, and mapping of human FGF8 with no evidence for its role in craniosynostosis/limb defect syndromes

19 March 2017

1 reference

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Structure and sequence of human FGF8

19 March 2017

1 reference

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The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo

19 March 2017

1 reference

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Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning

19 March 2017

1 reference

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Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse

19 March 2017

1 reference

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Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo

19 March 2017

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An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

19 March 2017

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Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism

7 April 2017

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Mutations in fibroblast growth factor receptor 1 cause Kallmann syndrome with a wide spectrum of reproductive phenotypes

27 September 2017

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Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism

27 September 2017

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Regulation of osteoblast differentiation: a novel function for fibroblast growth factor 8.

27 September 2017

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27 September 2017

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A window of opportunity: the diagnosis of gonadotropin deficiency in the male infant

27 September 2017

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Targeted expression of a dominant-negative fibroblast growth factor (FGF) receptor in gonadotropin-releasing hormone (GnRH) neurons reduces FGF responsiveness and the size of GnRH neuronal population

27 September 2017

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Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain

27 September 2017

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27 September 2017

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Digenic retinitis pigmentosa due to mutations at the unlinked peripherin/RDS and ROM1 loci

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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30 May 2018

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30 May 2018

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29 November 2018

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29 November 2018

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29 November 2018

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29 November 2018

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The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum.

29 November 2018

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29 November 2018

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29 November 2018

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29 November 2018

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The importance of autosomal genes in Kallmann syndrome: genotype-phenotype correlations and neuroendocrine characteristics.

29 November 2018

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29 November 2018

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The role of prior pubertal development, biochemical markers of testicular maturation, and genetics in elucidating the phenotypic heterogeneity of idiopathic hypogonadotropic hypogonadism

29 November 2018

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12 December 2020

Induction of puberty in men by long-term pulsatile administration of low-dose gonadotropin-releasing hormone

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12 December 2020

Osteoporosis in men with hyperprolactinemic hypogonadism

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12 December 2020

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12 December 2020

Adult-onset idiopathic hypogonadotropic hypogonadism--a treatable form of male infertility

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12 December 2020

Overlapping expression and redundant activation of mesenchymal fibroblast growth factor (FGF) receptors by alternatively spliced FGF-8 ligands

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12 December 2020

Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): pathophysiological and genetic considerations

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12 December 2020

Free alpha-subunit is superior to luteinizing hormone as a marker of gonadotropin-releasing hormone despite desensitization at fast pulse frequencies

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12 December 2020

Genomic structure, sequence, and mapping of humanFGF8 with no evidence for its role in craniosynostosis/limb defect syndromes

1 reference

Crossref

https://api.crossref.org/works/10.1172%2FJCI34538

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1172/JCI34538

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18596921%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18596921%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

2 references