Il-21 enhances NK cell activation and cytolytic activity and induces Th17 cell differentiation in inflammatory bowel disease (Q24309586)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19322899%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

Il-21 enhances NK cell activation and cytolytic activity and induces Th17 cell differentiation in inflammatory bowel disease (English)

1 reference

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inflammatory bowel diseases

24 January 2020

main subject

0 references

Interleukin 21

1 reference

positive regulation of cytokine production

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

5

1 reference

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24 January 2020

author name string

Zhanju Liu

1

1 reference

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24 January 2020

Li Yang

2

1 reference

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24 January 2020

Yi Cui

3

1 reference

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24 January 2020

Xingpeng Wang

4

1 reference

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24 January 2020

Zhigang Huang

6

1 reference

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24 January 2020

Quancheng Kan

7

1 reference

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24 January 2020

Zhangsuo Liu

8

1 reference

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24 January 2020

Yulan Liu

9

1 reference

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24 January 2020

language of work or name

English

0 references

publication date

1 August 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19322899%20AND%20SRC:MED&resulttype=core&format=json

Inflammatory Bowel Diseases

24 January 2020

published in

1 reference

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24 January 2020

volume

15

1 reference

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24 January 2020

issue

8

1 reference

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24 January 2020

page(s)

1133-1144

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Progress in basic inflammatory bowel disease research

24 January 2020

cites work

1 reference

Unravelling the pathogenesis of inflammatory bowel disease

21 January 2018

1 reference

Lymphocyte homing and its role in the pathogenesis of IBD.

21 January 2018

1 reference

Bacteria- and host-derived mechanisms to control intestinal epithelial cell homeostasis: implications for chronic inflammation

21 January 2018

1 reference

New players in the cytokine orchestra of inflammatory bowel disease

21 January 2018

1 reference

Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation

21 January 2018

1 reference

Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

21 January 2018

1 reference

Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

21 January 2018

1 reference

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

21 January 2018

1 reference

IL-21 and TGF-beta are required for differentiation of human T(H)17 cells

21 January 2018

1 reference

Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells

21 January 2018

1 reference

IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo

21 January 2018

1 reference

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

21 January 2018

1 reference

A critical role for IL-21 in regulating immunoglobulin production

21 January 2018

1 reference

Expression of interleukin-21 receptor in epidermis from patients with systemic sclerosis

21 January 2018

1 reference

Expression of interleukin-21 receptor, but not interleukin-21, in synovial fibroblasts and synovial macrophages of patients with rheumatoid arthritis

21 January 2018

1 reference

Interleukin-21 induces T-cell activation and proinflammatory cytokine secretion in rheumatoid arthritis

21 January 2018

1 reference

Interleukin-21 enhances T-helper cell type I signaling and interferon-gamma production in Crohn's disease

21 January 2018

1 reference

Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21.

21 January 2018

1 reference

Increased expression of interleukin 17 in inflammatory bowel disease

21 January 2018

1 reference

Phenotypic and functional features of human Th17 cells

21 January 2018

1 reference

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

21 January 2018

1 reference

Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

21 January 2018

1 reference

IL-21 signaling is critical for the development of type I diabetes in the NOD mouse

21 January 2018

1 reference

Regulation of gut inflammation and th17 cell response by interleukin-21.

21 January 2018

1 reference

21 January 2018

1 reference

Activation of RegIIIbeta/gamma and interferon gamma expression in the intestinal tract of SCID mice: an innate response to bacterial colonisation of the gut.

21 January 2018

1 reference

Lamina propria c-kit+ immune precursors reside in human adult intestine and differentiate into natural killer cells.

21 January 2018

1 reference

Leukocyte adhesion molecules in animal models of inflammatory bowel disease

21 January 2018

1 reference

Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis

21 January 2018

1 reference

7 January 2021

Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status

1 reference

7 January 2021

Blockage of tumor necrosis factor prevents intestinal mucosal inflammation through down-regulation of interleukin-23 secretion

1 reference

7 January 2021

Human small-intestinal epithelium contains functional natural killer lymphocytes

1 reference

7 January 2021

A Functional Role for Interleukin-21 in Promoting the Synthesis of the T-Cell Chemoattractant, MIP-3α, by Gut Epithelial Cells

1 reference

7 January 2021

IL-15 is highly expressed in inflammatory bowel disease and regulates local T cell-dependent cytokine production

1 reference

7 January 2021

IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response

1 reference

7 January 2021

Differential effects of IL-21 during initiation and progression of autoimmunity against neuroantigen

1 reference

7 January 2021

IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells.

1 reference

7 January 2021

Interleukin-21 enhances NK cell activation in response to antibody-coated targets

1 reference

7 January 2021

IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression.

1 reference

7 January 2021

IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis.

1 reference

7 January 2021

Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration

1 reference

7 January 2021

Identifiers

DOI

10.1002/IBD.20923

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19322899%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19322899%20AND%20SRC:MED&resulttype=core&format=json