Erythrocytosis-associated HIF-2alpha mutations demonstrate a critical role for residues C-terminal to the hydroxylacceptor proline (Q24309788)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Erythrocytosis-associated HIF-2alpha mutations demonstrate a critical role for residues C-terminal to the hydroxylacceptor proline (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

0 references

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Mary Frances McMullin

5

object named as

Mary Frances McMullin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

author name string

Paul W Furlow

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Melanie J Percy

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Scott Sutherland

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Charlene Bierl

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Stephen R Master

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Terence R J Lappin

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

language of work or name

English

0 references

publication date

10 February 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

21 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

volume

284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

page(s)

9050-9058

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

issue

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

Novel exon 12 mutations in the HIF2A gene associated with erythrocytosis

21 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

A gain-of-function mutation in the HIF2A gene in familial erythrocytosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1alpha activity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Dynamic, site-specific interaction of hypoxia-inducible factor-1alpha with the von Hippel-Lindau tumor suppressor protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Oxygen sensing by HIF hydroxylases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

The human oxygen sensing machinery and its manipulation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Genetic causes of erythrocytosis and the oxygen-sensing pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Erythropoietin after a century of research: younger than ever

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Hypoxia-inducible factors: central regulators of the tumor phenotype

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Oxygen sensing: recent insights from idiopathic erythrocytosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Von Hippel-Lindau-dependent polycythemia is endemic on the island of Ischia: identification of a novel cluster.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Congenital polycythemias/erythrocytoses.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Mutations of von Hippel-Lindau tumor-suppressor gene and congenital polycythemia.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

27 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808737200

Von Hippel-Lindau disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808737200

Familial erythrocytosis: molecular links to red blood cell control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808737200

Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2 alpha mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808737200

Characterization of ankyrin repeat-containing proteins as substrates of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808737200

Disturbance in the HIF-1alpha pathway associated with erythrocytosis: further evidences brought by frameshift and nonsense mutations in the prolyl hydroxylase domain protein 2 (PHD2) gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808737200

Mutations in the von Hippel-Lindau (VHL) tumor suppressor gene and VHL-haplotype analysis in patients with presumable congenital erythrocytosis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666553

Chuvash-type congenital polycythemia in 4 families of Asian and Western European ancestry

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19208626

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

10 Posttranslational enzymes in the biosynthesis of collagen: Intracellular enzymes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19208626

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The HIF2A gene in familial erythrocytosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19208626

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M808737200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19208626%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference