The promoters for human DNA-PKcs (PRKDC) and MCM4: divergently transcribed genes located at chromosome 8 band q11 (Q24310169)

GOA release 2020-03-11

DNA replication

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GOA release 2020-03-11

author name string

M A Connelly

1

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H Zhang

2

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J Kieleczawa

3

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C W Anderson

The Schizosaccharomyces pombe rad3 checkpoint gene

4

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language of work or name

English

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publication date

1 January 1998

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published in

Genomics

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volume

47

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issue

1

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page(s)

71-83

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cites work

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Sequence of the WT1 upstream region including the Wit-1 gene.

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Genomic structure and chromosomal assignment of the mouse Ku70 gene

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Use of T7 RNA polymerase to direct expression of cloned genes

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The organization and expression of histone gene families

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The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

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When is a lipid kinase not a lipid kinase? When it is a protein kinase

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Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

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DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

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Differential effects of DNA-binding proteins on bidirectional transcription from the common promoter region of human collagen type IV genes COL4A1 and COL4A2.

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The distribution of genes in the human genome

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Alternate splice-site utilization in the gene for the catalytic subunit of the DNA-activated protein kinase, DNA-PKcs

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Nomenclature of human genes involved in ionizing radiation sensitivity.

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Human genome organization

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Promoter-specific activation of RNA polymerase II transcription by Sp1

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New metal chelate adsorbent selective for proteins and peptides containing neighbouring histidine residues

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Basic local alignment search tool

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Transcription initiation from TATA-less promoters within eukaryotic protein-coding genes

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Generality of a functional initiator consensus sequence

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Cell cycle control of eukaryotic DNA replication.

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DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK.

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The scid mutation in mice causes a general defect in DNA repair

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A mammalian protein targeted by G1-arresting rapamycin-receptor complex

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Alpha 1(IV) and alpha 2(IV) collagen genes are regulated by a bidirectional promoter and a shared enhancer

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scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair

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Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II

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DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA.

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Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

A conserved downstream element defines a new class of RNA polymerase II promoters

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Analysis of the ChickenGPAT/AIRCBidirectional Promoter forde NovoPurine Nucleotide Synthesis

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7 January 2021

Absence of autoantigen Ku in mature human neutrophils and human promyelocytic leukemia line (HL-60) cells and lymphocytes undergoing apoptosis

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

A gene transcribed from the bidirectional ATM promoter coding for a serine rich protein: amino acid sequence, structure and expression studies

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

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Isolation and characterisation of the NBR2 gene which lies head to head with the human BRCA1 gene

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

A survey on intron and exon lengths

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Compilation of vertebrate-encoded transcription factors

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Ataxia-telangiectasia: structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expression

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Analysis of the DNA-binding and activation properties of the human transcription factor AP-2

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Identification and characterization of a new gene physically linked to the ATM gene

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Construction of mouse A9 clones containing a single human chromosome tagged with neomycin-resistance gene via microcell fusion

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Tissue, developmental, and tumor-specific expression of divergent transcripts in Wilms tumor

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

1 reference

https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

1 reference

https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

1 reference

https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

1 reference

https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

A DNA-activated protein kinase from HeLa cell nuclei

1 reference

https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

1 reference

https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Coexpression of two closely linked avian genes for purine nucleotide synthesis from a bidirectional promoter

1 reference

https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

DNA sequence requirements for transcriptional initiator activity in mammalian cells

1 reference

https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle

1 reference

https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Dual bidirectional promoters at the mouse dhfr locus: cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 gene

1 reference

https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

The SCID mouse mutant: definition, characterization, and potential uses

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https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

MCM4 and PRKDC, human genes encoding proteins MCM4 and DNA-PKcs, are close neighbours located on chromosome 8q12-->q13.

1 reference

https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021

Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap

1 reference

https://api.crossref.org/works/10.1006%2FGENO.1997.5076

7 January 2021