The E3 ligase TRAF6 regulates Akt ubiquitination and activation (Q24310343)

protein K63-linked ubiquitination

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

protein ubiquitination

1 reference

Wei-Lei Yang

1

Wei-Lei

Yang

1 reference

19 October 2023

Jing Wang

2

Jing

Wang

1 reference

19 October 2023

Chia-Hsin Chan

3

Chia-Hsin

Chan

1 reference

19 October 2023

Szu-Wei Lee

4

Szu-Wei

Lee

1 reference

19 October 2023

Alejandro D Campos

5

Alejandro D

Campos

1 reference

19 October 2023

Betty Lamothe

6

Betty

Lamothe

1 reference

19 October 2023

Lana Hur

7

Lana

Hur

1 reference

19 October 2023

Brian C Grabiner

8

Brian C

Grabiner

1 reference

19 October 2023

Xin Lin

9

Xin

Lin

1 reference

19 October 2023

Bryant G Darnay

10

Bryant G

Darnay

1 reference

19 October 2023

Hui-Kuan Lin

11

Hui-Kuan

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

Lin

1 reference

19 October 2023

language of work or name

English

0 references

publication date

28 August 2009

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published in

Science

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volume

325

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issue

5944

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page(s)

1134-8

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

The phosphoinositide 3-kinase pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

Mechanisms underlying ubiquitination

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

Proteasome-independent functions of ubiquitin in endocytosis and signaling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

TRAF6 is a signal transducer for interleukin-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

Cellular survival: a play in three Akts

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

Ubiquitin signalling in the NF-kappaB pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

Phosphoinositide 3-kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

Targeting the PI3K-Akt pathway in human cancer: rationale and promise

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

PKB binding proteins. Getting in on the Akt.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

Akt activation by growth factors is a multiple-step process: the role of the PH domain

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3008763

Tissue-specific mRNA expression profiles of human toll-like receptors and related genes

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1175065

Molecular modeling studies of the Akt PH domain and its interaction with phosphoinositides

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1175065

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1175065

1 reference

release_uriwt46hfnh53dxlucljcmsj7e

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1545053

1 reference

1 reference

1 reference