Low-Dose Cadmium Exposure Reduces Human Prostate Cell Transformation in Culture and Up-Regulates Metallothionein and MT-1G mRNA (Q24310858)

cellular response to cadmium ion

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Jaya P Gaddipati

1

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N V Rajeshkumar

2

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Jason C Grove

3

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Susan V M Maharaj

4

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Jose A Centeno

5

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Radha K Maheshwari

6

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Wayne B Jonas

Nonlinearity in biology, toxicology, medicine

7

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language of work or name

English

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publication date

April 2003

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published in

1 reference

Isoform-specific expression of metallothionein mRNA in the developing and adult human kidney

volume

1

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issue

2

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page(s)

199-212

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cites work

1 reference

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MT-III, a brain-specific member of the metallothionein gene family

19 March 2017

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Metallothionein isoform 1 and 2 gene expression in the human prostate: downregulation of MT-1X in advanced prostate cancer

19 March 2017

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Characterisation of six additional human metallothionein genes

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Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia

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Human metallothionein genes: structure of the functional locus at 16q13

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Altered apoptotic gene expression and acquired apoptotic resistance in cadmium-transformed human prostate epithelial cells

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Cadmium-induced malignant transformation of human prostate epithelial cells

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Cadmium induces c-myc, p53, and c-jun expression in normal human prostate epithelial cells as a prelude to apoptosis

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Pattern of stress protein expression in human lung cell-line A549 after short- or long-term exposure to cadmium

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Metallothionein: an intracellular protein to protect against cadmium toxicity

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Role of metallothionein in cadmium-induced hepatotoxicity and nephrotoxicity

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Metallothionein induction and deinduction in human prostatic carcinoma cells: relationship with resistance and sensitivity to adriamycin

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Hormesis: a stress response in cells exposed to low levels of heavy metals

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Metallothionein isoform 1 and 2 gene expression in the human prostate: Downregulation of MT-1X in advanced prostate cancer

21 January 2018

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Dietary cadmium inhibits spontaneous hepatocarcinogenesis in C3H/HeN mice and hepatitis in A/J mice, but not in C57BL/6 mice.

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Down-regulation of metallothionein expression in human and murine hepatocellular tumors: association with the tumor-necrotizing and antineoplastic effects of cadmium in mice.

21 January 2018

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Anticarcinogenic effects of cadmium in B6C3F1 mouse liver and lung

29 November 2018

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12 December 2020

Occupation, cadmium exposure, and prostate cancer

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12 December 2020

Evaluation of the Cd/hemoglobin affinity assay for the rapid determination of metallothionein in biological tissues

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12 December 2020

Cadmium acclimation and hormesis in Fundulus heteroclitus during fin regeneration

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12 December 2020

The hormetic dose-response model is more common than the threshold model in toxicology

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12 December 2020

Increased resistance against cadmium toxicity by means of pretreatment with low cadmium/zinc concentrations in Bufo arenarum embryos

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12 December 2020