Structural basis for the recognition of c-Src by its inactivator Csk (Q24311447)

4

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Markus A Seeliger

object named as

Markus A Seeliger

2

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author name string

Nicholas M Levinson

1

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Philip A Cole

An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

3

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language of work or name

English

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publication date

11 July 2008

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published in

Cell

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volume

134

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issue

1

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page(s)

124-34

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cites work

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Overexpressed Csk tyrosine kinase is localized in focal adhesions, causes reorganization of alpha v beta 5 integrin, and interferes with HeLa cell spreading

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A Molecular Brake in the Kinase Hinge Region Regulates the Activity of Receptor Tyrosine Kinases

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Structure of a c-kit product complex reveals the basis for kinase transactivation

19 March 2017

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Structure of the carboxyl-terminal Src kinase, Csk

19 March 2017

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Structure and autoregulation of the insulin-like growth factor 1 receptor kinase

19 March 2017

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Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors

19 March 2017

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Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor

19 March 2017

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Crystal structures of c-Src reveal features of its autoinhibitory mechanism

19 March 2017

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Structure of the protein tyrosine kinase domain of C-terminal Src kinase (CSK) in complex with staurosporine

19 March 2017

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Crystal structure of the Src family tyrosine kinase Hck

19 March 2017

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Three-dimensional structure of the tyrosine kinase c-Src

19 March 2017

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Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

19 March 2017

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19 March 2017

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19 March 2017

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PHENIX: building new software for automated crystallographic structure determination

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

19 March 2017

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Structure and chemical inhibition of the RET tyrosine kinase domain

19 March 2017

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A Src-like inactive conformation in the abl tyrosine kinase domain

19 March 2017

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CSK: a protein-tyrosine kinase involved in regulation of src family kinases

19 March 2017

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Regulation of protein kinases; controlling activity through activation segment conformation

19 March 2017

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Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

7 April 2017

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Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

7 April 2017

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Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

7 April 2017

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Regulation, substrates and functions of src

7 April 2017

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On the importance of a funneled energy landscape for the assembly and regulation of multidomain Src tyrosine kinases

10 May 2017

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C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases

27 September 2017

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Structure of human Fyn kinase domain complexed with staurosporine

27 September 2017

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Docking-based substrate recognition by the catalytic domain of a protein tyrosine kinase, C-terminal Src kinase (Csk).

27 September 2017

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High yield bacterial expression of active c-Abl and c-Src tyrosine kinases

27 September 2017

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The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation

27 September 2017

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Probing the communication between the regulatory and catalytic domains of a protein tyrosine kinase, Csk.

27 September 2017

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The use of recombinant methods and molecular engineering in protein crystallization

27 September 2017

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Determination of the substrate-docking site of protein tyrosine kinase C-terminal Src kinase

27 September 2017

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Determinants of substrate recognition in nonreceptor tyrosine kinases

27 September 2017

1 reference

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Molecular determinants for Csk-catalyzed tyrosine phosphorylation of the Src tail

27 September 2017

1 reference

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Why cytoplasmic signalling proteins should be recruited to cell membranes.

27 September 2017

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Identification of residues involved in v-Src substrate recognition by site-directed mutagenesis

27 September 2017

1 reference

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Domain interactions in protein tyrosine kinase Csk.

27 September 2017

1 reference

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Mutations in the N-terminal regulatory region reduce the catalytic activity of Csk, but do not affect its recognition of Src.

27 September 2017

1 reference

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Peptide and protein phosphorylation by protein tyrosine kinase Csk: insights into specificity and mechanism

27 September 2017

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Analysis of human c-Abl tyrosine kinase activity and regulation in S. pombe.

27 September 2017

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The nonreceptor protein-tyrosine kinase CSK complexes directly with the GTPase-activating protein-associated p62 protein in cells expressing v-Src or activated c-Src

27 September 2017

1 reference

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Csk suppression of Src involves movement of Csk to sites of Src activity

27 September 2017

1 reference

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Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src

27 September 2017

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Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus

27 September 2017

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Crystal structures of active SRC kinase domain complexes

27 September 2017

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Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog

30 May 2018

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Substrate specificity of the oncoprotein v-Fps: site-specific mutagenesis of the putative P+1 pocket

30 May 2018

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SRC tail phosphorylation is limited by structural changes in the regulatory tyrosine kinase Csk.

30 May 2018

1 reference

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Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680.

29 November 2018

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Coupled motions in the SH2 and kinase domains of Csk control Src phosphorylation

29 November 2018

1 reference

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Phosphoryl transfer step in the C-terminal Src kinase controls Src recognition

29 November 2018

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A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase.

29 November 2018

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Dynamic coupling between the SH2 domain and active site of the COOH terminal Src kinase, Csk.

29 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494536

Regulation of c-Fes tyrosine kinase activity by coiled-coil and SH2 domains: analysis with Saccharomyces cerevisiae

29 November 2018

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Functions of the activation loop in Csk protein-tyrosine kinase

29 November 2018

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Engineering the substrate specificity of the Abl tyrosine kinase

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PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

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