Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma (Q24311457)

9

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author name string

Tobias Otto

1

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Sebastian Horn

2

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Markus Brockmann

3

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Ursula Eilers

4

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Lars Schüttrumpf

5

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Nikita Popov

6

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Anna Marie Kenney

7

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Johannes H Schulte

8

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Holger Christiansen

10

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Bernd Berwanger

MYCN regulates oncogenic MicroRNAs in neuroblastoma

11

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language of work or name

English

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publication date

6 January 2009

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published in

Cancer Cell

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volume

15

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page(s)

67-78

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issue

1

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cites work

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Differentiation and apoptosis of neuroblastoma cells: role of N-myc gene product

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Oncogenic cooperation between H-Twist and N-Myc overrides failsafe programs in cancer cells.

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The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation

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A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size

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The Cdk1 complex plays a prime role in regulating N-myc phosphorylation and turnover in neural precursors.

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Conditional transgenic models define how MYC initiates and maintains tumorigenesis

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Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

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Genetic parameters of neuroblastomas

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Skp2 regulates Myc protein stability and activity

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Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma

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Multiple cell-type-specific elements regulate Myc protein stability

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Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

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The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

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