The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix (Q24311587)

9

0 references

Christiane Garbay

6

0 references

Michel Vidal

object named as

Michel Vidal

5

0 references

Joel L. Sussman

object named as

Joel L Sussman

7

0 references

author name string

Hay Dvir

1

0 references

Michal Harel

2

0 references

Suzanne Bon

3

0 references

Wang-Qing Liu

4

0 references

Jean Massoulié

Human endplate acetylcholinesterase deficiency caused by mutations in the collagen-like tail subunit (ColQ) of the asymmetric enzyme

8

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language of work or name

English

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publication date

10 November 2004

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published in

The EMBO Journal

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volume

23

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issue

22

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page(s)

4394-405

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cites work

1 reference

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NMR structure of the N-terminal SH3 domain of GRB2 and its complex with a proline-rich peptide from Sos

19 March 2017

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Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II

19 March 2017

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19 March 2017

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Conformational flexibility of the acetylcholinesterase tetramer suggested by x-ray crystallography

21 January 2018

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Acetylcholinesterase inhibition by fasciculin: crystal structure of the complex

19 March 2017

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Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

19 March 2017

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High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides

19 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

19 March 2017

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Automated refinement of protein models

19 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

19 March 2017

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19 March 2017

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Determination of macromolecular structures from anomalous diffraction of synchrotron radiation

22 April 2017

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Molecular and cellular biology of cholinesterases

19 March 2017

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Modes of attachment of acetylcholinesterase to the surface membrane

19 March 2017

1 reference

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Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein

19 March 2017

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PRiMA: the membrane anchor of acetylcholinesterase in the brain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Comparative genomics of the eukaryotes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Coiled coils: a highly versatile protein folding motif

7 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

A graphics model building and refinement system for macromolecules

7 April 2017

1 reference

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Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis

22 April 2017

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22 April 2017

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600425

Historical review: another 50th anniversary--new periodicities in coiled coils

21 January 2018

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Congenital myasthenic syndromes: multiple molecular targets at the neuromuscular junction.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

The structure of collagen

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

27 September 2017

Structure of collagen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Is alpha-keratin a coiled coil?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

The C-terminal T peptide of acetylcholinesterase enhances degradation of unassembled active subunits through the ERAD pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

The origin of the molecular diversity and functional anchoring of cholinesterases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Analysis of alpha-helical coiled coils with the program TWISTER reveals a structural mechanism for stutter compensation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Hierarchy of post-translational modifications involved in the circulatory longevity of glycoproteins. Demonstration of concerted contributions of glycan sialylation and subunit assembly to the pharmacokinetic behavior of bovine acetylcholinesterase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

A Sos-derived peptidimer blocks the Ras signaling pathway by binding both Grb2 SH3 domains and displays antiproliferative activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

A four-to-one association between peptide motifs: four C-terminal domains from cholinesterase assemble with one proline-rich attachment domain (PRAD) in the secretory pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Critical residues in an SH3 domain from Sem-5 suggest a mechanism for proline-rich peptide recognition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Molecular Structures of Acetylcholinesterase from Electric Organ Tissue of the Electric Eel

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Primary structure of a collagenic tail peptide of Torpedo acetylcholinesterase: co-expression with catalytic subunit induces the production of collagen-tailed forms in transfected cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

H and T subunits of acetylcholinesterase from Torpedo, expressed in COS cells, generate all types of globular forms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Molecular structure of elongated forms of electric eel acetylcholinesterase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

"Nonspecific" cholinesterase and acetylcholinesterase in rat tissues: molecular forms, structural and catalytic properties, and significance of the two enzyme systems

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Developmental Regulation of Acetylcholinesterase Transcripts in the Mouse Diaphragm: Alternative Splicing and Focalization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Tetramerization domain of human butyrylcholinesterase is at the C-terminus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

The mammalian gene of acetylcholinesterase-associated collagen

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Quaternary associations of acetylcholinesterase. II. The polyproline attachment domain of the collagen tail

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

An Immunological Study of Rat Acetylcholinesterase: Comparison with Acetylcholinesterases from Other Vertebrates

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Identification of discrete disulfide-linked oligomers which distinguish 18 S from 14 S acetylcholinesterase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Left-handed polyproline II helices commonly occur in globular proteins.

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600425

HELANAL: a program to characterize helix geometry in proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600425

Elements of the C-terminal t peptide of acetylcholinesterase that determine amphiphilicity, homomeric and heteromeric associations, secretion and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600425

The packing of α-helices: simple coiled-coils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600425

Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600425

A Novel Scoring Function for Predicting the Conformations of Tightly Packed Pairs of Transmembrane α-Helices

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600425

Effective electron-density map improvement and structure validation on a Linux multi-CPU web cluster: The TB Structural Genomics Consortium Bias Removal Web Service

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600425

Generalized method of determining heavy-atom positions using the difference Patterson function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600425

A structure-factor least-squares refinement procedure for macromolecular structures using constrainedandrestrained parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600425

The C-terminal t peptide of acetylcholinesterase forms an alpha helix that supports homomeric and heteromeric interactions

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=526459

Molecular forms of Electrophorus acetylcholinesterase the catalytic subunits: fragmentation, intra- and inter-subunit disulfide bonds

29 November 2018

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12 December 2020

Converging on proline: the mechanism of WW domain peptide recognition

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12 December 2020

Acetylcholinesterase H and T dimers are associated through the same contact. Mutations at this interface interfere with the C-terminal T peptide, inducing degradation rather than secretion

1 reference

12 December 2020

Trimerization domain of the collagen tail of acetylcholinesterase

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

Acetylcholinesterase from bovine caudate nucleus is attached to membranes by a novel subunit distinct from those of acetylcholinesterases in other tissues

1 reference

12 December 2020

Tetrameric detergent-soluble acetylcholinesterase from human caudate nucleus: subunit composition and number of active sites

1 reference

12 December 2020

[Electron microscopic studies on stretched and globular acetylcholinesterase molecules of the electric eel (Electrophorus electricus)]

1 reference

12 December 2020

Parallel regulation of acetylcholinesterase and pseudocholinesterase in normal, denervated and dystrophic chicken skeletal muscle

1 reference

12 December 2020

Molecular forms of the cholinesterases inside and outside muscle endplates

1 reference

12 December 2020

Quaternary associations of acetylcholinesterase. I. Oligomeric associations of T subunits with and without the amino-terminal domain of the collagen tail

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7600425

1 reference

1 reference

1 reference

PubMed publication ID

15526038

1 reference