Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation (Q24311960)

identical protein binding

GOA release 2020-03-11

1 reference

Transthyretin mutations in hyperthyroxinemia and amyloid diseases

GOA release 2020-03-11

1 reference

Nelson Ferreira

1

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Maria Rosário Almeida

object named as

Maria Rosário Almeida

series ordinal

3

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Maria João Saraiva

object named as

Maria João Saraiva

series ordinal

2

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language of work or name

English

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publication date

4 August 2011

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published in

FEBS Letters

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volume

585

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issue

15

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page(s)

2424-30

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cites work

1 reference

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The molecular biology and clinical features of amyloid neuropathy

21 January 2018

1 reference

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Transthyretin Pro55, a variant associated with early-onset, aggressive, diffuse amyloidosis with cardiac and neurologic involvement

21 January 2018

1 reference

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Partial denaturation of transthyretin is sufficient for amyloid fibril formation in vitro

21 January 2018

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Structure-based design of kinetic stabilizers that ameliorate the transthyretin amyloidoses

21 January 2018

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Evaluating the binding selectivity of transthyretin amyloid fibril inhibitors in blood plasma

21 January 2018

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4 ′‐iodo‐4′‐Deoxydoxorubicin and tetracyclines disrupt transthyretin amyloid fibrils in vitro producing noncytotoxic species: screening for TTR fibril disrupters

21 January 2018

1 reference

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Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative

21 January 2018

1 reference

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Binding of epigallocatechin-3-gallate to transthyretin modulates its amyloidogenicity

21 January 2018

1 reference

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Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

21 January 2018

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Antioxidant compounds have potent anti-fibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro

21 January 2018

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Comparative in vitro and ex vivo activities of selected inhibitors of transthyretin aggregation: relevance in drug design

21 January 2018

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Transthyretin oligomers induce calcium influx via voltage-gated calcium channels.

21 January 2018

1 reference

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Aromatic small molecules remodel toxic soluble oligomers of amyloid beta through three independent pathways

21 January 2018

1 reference

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Binding and stabilization of transthyretin by curcumin.

21 January 2018

1 reference

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The crystal structure of the green tea polyphenol (-)-epigallocatechin gallate-transthyretin complex reveals a novel binding site distinct from the thyroxine binding site

21 January 2018

1 reference

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Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model

21 January 2018

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EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

21 January 2018

1 reference

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Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model.

21 January 2018

1 reference

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Curcumin as "Curecumin": from kitchen to clinic.

21 January 2018

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The Tetrameric Protein Transthyretin Dissociates to a Non-native Monomer in Solution

21 January 2018

1 reference

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Search for intermediate structures in transthyretin fibrillogenesis: soluble tetrameric Tyr78Phe TTR expresses a specific epitope present only in amyloid fibrils

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: evidence for toxicity of nonfibrillar aggregates

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.06.030

inferred from DOI database lookup

7 January 2021

based on heuristic

The crystal structure of amyloidogenic Leu55 --> Pro transthyretin variant reveals a possible pathway for transthyretin polymerization into amyloid fibrils

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.06.030