Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling (Q24312963)

Parkin RBR E3 ubiquitin protein ligase

GOA release 2020-03-11

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GOA release 2020-03-11

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6

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Olga Corti

object named as

Olga Corti

2

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Ernest Arenas

object named as

Ernest Arenas

7

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author name string

Nina Rawal

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Paola Sacchetti

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Hector Ardilla-Osorio

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Bita Sehat

Biochemical and Biophysical Research Communications

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language of work or name

English

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publication date

23 October 2009

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published in

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volume

388

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issue

3

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page(s)

473-8

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cites work

Parkin gene alterations in hepatocellular carcinoma

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Immortalization of embryonic mesencephalic dopaminergic neurons by somatic cell fusion

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Wnt signaling in lung cancer

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Dynamic temporal and cell type-specific expression of Wnt signaling components in the developing midbrain

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RING finger proteins: mediators of ubiquitin ligase activity

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How the cyclin became a cyclin: regulated proteolysis in the cell cycle

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Differential expression and tissue distribution of parkin isoforms during mouse development

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Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path?

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Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity

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Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses

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Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

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Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

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WNTs in the vertebrate nervous system: from patterning to neuronal connectivity

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How does parkin ligate ubiquitin to Parkinson's disease?

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Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 gene

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Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a

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Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin

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Modulation of beta-catenin phosphorylation/degradation by cyclin-dependent kinase 2.

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An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

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Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse

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Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity

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Kainic acid-induced apoptosis in cerebellar granule neurons: an attempt at cell cycle re-entry

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Proteomic analysis of parkin knockout mice: alterations in energy metabolism, protein handling and synaptic function

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Alterations of the tumor suppressor gene Parkin in non-small cell lung cancer

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The Wnt signalling pathway

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GSK-3beta inhibition/beta-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons

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Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.

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Wnt/Frizzled signaling in hepatocellular carcinoma

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