Myocilin mediates myelination in the peripheral nervous system through ErbB2/3 signaling (Q24313038)

Erb-b2 receptor tyrosine kinase 3

1 reference

Neuronal cell adhesion molecule

1 reference

Myocilin

1 reference

Neurofascin

1 reference

Gliomedin

1 reference

1 reference

Thomas V Johnson

2

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Mones Abu-Asab

object named as

Mones Abu-Asab

4

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author name string

Heung Sun Kwon

1

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Myung Kuk Joe

3

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Jun Zhang

5

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Chi Chao Chan

6

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Stanislav I Tomarev

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

13 September 2013

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published in

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volume

288

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issue

37

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page(s)

26357-71

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describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3772183/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1

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Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin

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A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier

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Myocilin interacts with syntrophins and is member of dystrophin-associated protein complex

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Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination

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Neuregulin-1 type III determines the ensheathment fate of axons

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Secreted glycoprotein myocilin is a component of the myelin sheath in peripheral nerves

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Expression of neuregulins and their putative receptors, ErbB2 and ErbB3, is induced during Wallerian degeneration

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ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms

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Expression of myocilin mutants sensitizes cells to oxidative stress-induced apoptosis: implication for glaucoma pathogenesis

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Secreted gliomedin is a perinodal matrix component of peripheral nerves

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Myocilin mutations causing glaucoma inhibit the intracellular endoproteolytic cleavage of myocilin between amino acids Arg226 and Ile227.

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Genetically increasing Myoc expression supports a necessary pathologic role of abnormal proteins in glaucoma

27 September 2017

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Laminin gamma1 is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerve

27 September 2017

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Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function

27 September 2017

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27 September 2017

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27 September 2017

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Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.

27 September 2017

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Schwann cell myelination occurred without basal lamina formation in laminin alpha2 chain-null mutant (dy3K/dy3K) mice

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772183

Characterization of the mouse Myoc/Tigr gene.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772183

Analysis of myocilin mutations in 1703 glaucoma patients from five different populations

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1 reference

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Recurrent mutations in a single exon encoding the evolutionarily conserved olfactomedin-homology domain of TIGR in familial open-angle glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.446138

Molecular and clinical evaluation of a patient hemizygous for TIGR/MYOC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.446138

Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.446138

Mutated mouse and human myocilins have similar properties and do not block general secretory pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.446138

The ABCA1 cholesterol transporter associates with one of two distinct dystrophin-based scaffolds in Schwann cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.446138

Disruption of neurofascin and gliomedin at nodes of Ranvier precedes demyelination in experimental allergic neuritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.446138

Primary open-angle glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.446138

Truncations in the TIGR gene in individuals with and without primary open-angle glaucoma

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23897819

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Schwann cells stimulated to proliferate in the absence of neurons retain full functional capability

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23897819

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.446138

1 reference

1 reference

1 reference

PubMed publication ID

23897819

1 reference