An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression (Q24313269)

Qi Cao

4

0 references

Ming Hu

Ming Hu

Sooryanarayana Varambally

10

0 references

Sooryanarayana Varambally

22

0 references

Zhaohui Steve Qin

Zhaohui S Qin

23

0 references

author name string

Jindan Yu

1

0 references

Jianjun Yu

2

0 references

Ram-Shankar Mani

3

0 references

Chad J Brenner

5

0 references

Xuhong Cao

6

0 references

Xiaoju Wang

7

0 references

James Li

9

0 references

Yusong Gong

11

0 references

Hong Cheng

12

0 references

Bharathi Laxman

13

0 references

Adaikkalam Vellaichamy

14

0 references

Sunita Shankar

15

0 references

Yong Li

16

0 references

Saravana M Dhanasekaran

17

0 references

Roger Morey

18

0 references

Terrence Barrette

19

0 references

Robert J Lonigro

20

0 references

Scott A Tomlins

21

0 references

Arul M Chinnaiyan

An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB

24

0 references

language of work or name

English

0 references

publication date

18 May 2010

0 references

published in

Cancer Cell

0 references

volume

17

0 references

page(s)

443-54

0 references

issue

5

0 references

cites work

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Three-color FISH analysis of TMPRSS2/ERG fusions in prostate cancer indicates that genomic microdeletion of chromosome 21 is associated with rearrangement

19 March 2017

1 reference

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19 March 2017

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Role of the TMPRSS2-ERG gene fusion in prostate cancer

19 March 2017

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7 April 2017

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The polycomb group protein EZH2 is involved in progression of prostate cancer

7 April 2017

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7 April 2017

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Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

27 September 2017

1 reference

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ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells

27 September 2017

1 reference

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Phase 1 trial of high-dose exogenous testosterone in patients with castration-resistant metastatic prostate cancer

27 September 2017

1 reference

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Genomic androgen receptor-occupied regions with different functions, defined by histone acetylation, coregulators and transcriptional capacity

27 September 2017

1 reference

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Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts

27 September 2017

1 reference

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A causal role for ERG in neoplastic transformation of prostate epithelium.

27 September 2017

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A polycomb repression signature in metastatic prostate cancer predicts cancer outcome

27 September 2017

1 reference

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Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer

27 September 2017

1 reference

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Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex

27 September 2017

1 reference

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New androgen receptor genomic targets show an interaction with the ETS1 transcription factor.

27 September 2017

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A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth

27 September 2017

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Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

27 September 2017

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TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer

27 September 2017

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Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis

27 September 2017

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Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer

27 September 2017

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Ets proteins in biological control and cancer

27 September 2017

1 reference

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The role of antiandrogen monotherapy in the treatment of prostate cancer

27 September 2017

1 reference

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Molecular biology of the Ets family of transcription factors

27 September 2017

1 reference

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Regulation of alkaline phosphatase promoter activity by forkhead transcription factor FKHR.

27 September 2017

1 reference

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Tumor necrosis factor-alpha represses androgen sensitivity in the LNCaP prostate cancer cell line

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874722

Progression of LNCaP prostate tumor cells during androgen deprivation: hormone-independent growth, repression of proliferation by androgen, and role for p27Kip1 in androgen-induced cell cycle arrest

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874722

Interaction of murine ets-1 with GGA-binding sites establishes the ETS domain as a new DNA-binding motif

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874722

Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874722

ETS rearrangements and prostate cancer initiation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874722

TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874722

TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874722

Diversity of TMPRSS2-ERG fusion transcripts in the human prostate

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874722

Confirmation of the high frequency of the TMPRSS2/ERG fusion gene in prostate cancer.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874722

Androgen receptor represses the neuroendocrine transdifferentiation process in prostate cancer cells.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874722

Extinction of E-cadherin expression in breast cancer via a dominant repression pathway acting on proximal promoter elements

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20478527

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20478527

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CCR.2010.03.018

1 reference

1131210

1131210

1 reference

1 reference

1 reference