Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding (Q24313280)

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24 November 2019

title

Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993212%20AND%20SRC:MED&resulttype=core&format=json

Chromatin licensing and DNA replication factor 1

24 November 2019

main subject

phosphorylation

0 references

1 reference

GOA release 2020-03-11

author

Nozomi Sugimoto

1

1 reference

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24 November 2019

Yasutoshi Tatsumi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993212%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

Hideo Nishitani

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993212%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

Masatoshi Fujita

7

1 reference

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24 November 2019

author name string

Tatsuya Tsurumi

3

1 reference

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24 November 2019

Akio Matsukage

4

1 reference

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24 November 2019

Tohru Kiyono

5

1 reference

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24 November 2019

language of work or name

English

0 references

publication date

1 March 2004

1 reference

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Journal of Biological Chemistry

24 November 2019

published in

1 reference

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24 November 2019

volume

279

1 reference

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24 November 2019

issue

19

1 reference

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24 November 2019

page(s)

19691-19697

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DNA replication in eukaryotic cells

24 November 2019

cites work

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Uninterrupted MCM2-7 function required for DNA replication fork progression

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Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase

21 January 2018

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Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6

21 January 2018

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Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

21 January 2018

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Mutation of cyclin/cdk phosphorylation sites in HsCdc6 disrupts a late step in initiation of DNA replication in human cells

21 January 2018

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Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms

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Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

21 January 2018

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Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2

21 January 2018

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Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin

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Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk.

21 January 2018

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21 January 2018

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Construction by gene targeting in human cells of a "conditional' CDC2 mutant that rereplicates its DNA.

21 January 2018

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Cell cycle- and chromatin binding state-dependent phosphorylation of human MCM heterohexameric complexes. A role for cdc2 kinase.

21 January 2018

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Control of DNA replication and chromosome ploidy by geminin and cyclin A

21 January 2018

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Cell cycle regulation of human CDC6 protein. Intracellular localization, interaction with the human mcm complex, and CDC2 kinase-mediated hyperphosphorylation.

21 January 2018

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Nuclear organization of DNA replication initiation proteins in mammalian cells

21 January 2018

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Geminin, an inhibitor of DNA replication, is degraded during mitosis

21 January 2018

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XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis

21 January 2018

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The Cdt1 protein is required to license DNA for replication in fission yeast

21 January 2018

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Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

21 January 2018

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Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

21 January 2018

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The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase

21 January 2018

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Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

21 January 2018

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Requirement for p34cdc2 kinase is restricted to mitosis in the mammalian cdc2 mutant FT210

21 January 2018

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Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors

21 January 2018

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Cyclin-binding motifs are essential for the function of p21CIP1

21 January 2018

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The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation

21 January 2018

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Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity

21 January 2018

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Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A.

21 January 2018

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Delayed early embryonic lethality following disruption of the murine cyclin A2 gene.

21 January 2018

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Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero

21 January 2018

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Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice.

21 January 2018

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Unphosphorylatable mutants of Cdc6 disrupt its nuclear export but still support DNA replication once per cell cycle

21 January 2018

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Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint

21 January 2018

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hCDC47, a Human Member of the MCM Family

21 January 2018

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Cyclin A is required at two points in the human cell cycle

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

hCDC47, a human member of the MCM family. Dissociation of the nucleus-bound form during S phase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313175200

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.M313175200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993212%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

1 reference