Point mutations in v-Myb disrupt a cyclophilin-catalyzed negative regulatory mechanism (Q24313422)

transcription factor binding

GOA release 2020-03-11

1 reference

Modulation of c-Myb-induced transcription activation by a phosphorylation site near the negative regulatory domain

GOA release 2020-03-11

author name string

J D Leverson

series ordinal

1

0 references

S A Ness

series ordinal

2

0 references

language of work or name

English

0 references

publication date

January 1998

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published in

Molecular Cell

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volume

1

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issue

2

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page(s)

203-11

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cites work

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The EVES motif mediates both intermolecular and intramolecular regulation of c-Myb

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Oncogenic truncation of the first repeat of c-Myb decreases DNA binding in vitro and in vivo

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A cyclophilin function in Hsp90-dependent signal transduction

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Weak transcriptional activation is sufficient for transformation by v-Myb

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DNA-binding domain ancestry

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Molecular chaperone machines: chaperone activities of the cyclophilin Cyp-40 and the steroid aporeceptor-associated protein p23

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Degeneration of skeletal and cardiac muscles in c-myb transgenic mice

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Structure of the protein encoded by the chicken proto-oncogene c-myb

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Myb: a transcriptional activator linking proliferation and differentiation in hematopoietic cells.

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Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kappa B subunit

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Expression of human cyclophilin-40 and the effect of the His141-->Trp mutation on catalysis and cyclosporin A binding

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Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene.

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Characterization of the cooperative function of inhibitory sequences in Ets-1.

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Functional analysis of Met4, a yeast transcriptional activator responsive to S-adenosylmethionine.

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Cyclophilin-dependent stimulation of transcription by cyclosporin A

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Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation

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A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

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Casein kinase II phosphorylation site mutations in c-Myb affect DNA binding and transcriptional cooperativity with NF-M.

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The cyclosporin A-binding immunophilin CyP-40 and the FK506-binding immunophilin hsp56 bind to a common site on hsp90 and exist in independent cytosolic heterocomplexes with the untransformed glucocorticoid receptor

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Cyclosporin A potentiates the dexamethasone-induced mouse mammary tumor virus-chloramphenicol acetyltransferase activity in LMCAT cells: a possible role for different heat shock protein-binding immunophilins in glucocorticosteroid receptor-mediated

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Two modes of c-myb activation in virus-induced mouse myeloid tumors

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A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

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A dominant interfering Myb mutant causes apoptosis in T cells

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Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters

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Cyclophilin A and FKBP12 interact with YY1 and alter its transcriptional activity

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Activation of the DNA-binding ability of human heat shock transcription factor 1 may involve the transition from an intramolecular to an intermolecular triple-stranded coiled-coil structure

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