Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade (Q24314554)

intrinsic apoptotic signaling pathway

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

B Levkau

1

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H Koyama

2

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E W Raines

3

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B E Clurman

4

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B Herren

5

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K Orth

6

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J M Roberts

7

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R Ross

Study of the cell cycle-dependent assembly of the DNA pre-replication centres in Xenopus egg extracts.

8

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language of work or name

English

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publication date

March 1998

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published in

Molecular Cell

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volume

1

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page(s)

553-63

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issue

4

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cites work

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Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors

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Proteolysis and the biochemistry of life-or-death decisions

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Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1

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Reversal of terminal differentiation and control of DNA replication: cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication

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Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death

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Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

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Rescue from granzyme B-induced apoptosis by Wee1 kinase

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Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

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Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

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Protective role of p21(Waf1/Cip1) against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells

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Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA

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Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

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Cell cycle and apoptosis: common pathways to life and death.

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Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of Cdk2 inhibitors

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Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

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Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein

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In vitro and in vivo studies of ICE inhibitors

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Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

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Apoptosis and the cell cycle.

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Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases

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Activation of cyclin A-dependent protein kinases during apoptosis

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Principles of CDK regulation

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

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Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases.

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Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons

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Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport

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The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells

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Genetic determinants of p53-induced apoptosis and growth arrest

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Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells

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Caspases: intracellular signaling by proteolysis

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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

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Premature p34cdc2 activation required for apoptosis.

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Substrate specificities of caspase family proteases

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A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

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Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases

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Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation.

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A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen

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p21-containing cyclin kinases exist in both active and inactive states

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10.1016/S1097-2765(00)80055-6

Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

4038071

4038071

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference