Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters (Q24314812)

2

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Kristine M Frizzell

3

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Matthew J Gamble

4

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Michelle E DuMond

5

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Raga Krishnakumar

6

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Tianle Yang

7

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Anthony A Sauve

8

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W Lee Kraus

Journal of Biological Chemistry

9

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language of work or name

English

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publication date

24 July 2009

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published in

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volume

284

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page(s)

20408-17

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issue

30

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cites work

Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis

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SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

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Combinatorial patterns of histone acetylations and methylations in the human genome

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Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme

19 March 2017

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Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival

19 March 2017

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Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1

19 March 2017

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Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity

19 March 2017

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Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

19 March 2017

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A local mechanism mediates NAD-dependent protection of axon degeneration

19 March 2017

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Human retroviral gag- and gag-pol-like proteins interact with the transforming growth factor-beta receptor activin receptor-like kinase 1

19 March 2017

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Characterization of human brain nicotinamide 5′-mononucleotide adenylyltransferase-2 and expression in human pancreas

19 March 2017

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Characterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesis

19 March 2017

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Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase

19 March 2017

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Identification and cloning of neuroblastoma-specific and nerve tissue-specific genes through compiled expression profiles

19 March 2017

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19 March 2017

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NAD metabolism and sirtuins: metabolic regulation of protein deacetylation in stress and toxicity

19 March 2017

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Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription

19 March 2017

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Interaction of N-terminal acetyltransferase with the cytoplasmic domain of beta-amyloid precursor protein and its effect on A beta secretion

19 March 2017

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The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

19 March 2017

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Reconstructing eukaryotic NAD metabolism

19 March 2017

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Growth phase-dependent changes in the subcellular localization of pre-B-cell colony-enhancing factor

19 March 2017

1 reference

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Identification of a novel human nicotinamide mononucleotide adenylyltransferase

19 March 2017

1 reference

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Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening

19 March 2017

1 reference

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A retrotransposon-derived gene, PEG10, is a novel imprinted gene located on human chromosome 7q21

19 March 2017

1 reference

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Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

19 March 2017

1 reference

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Sirtuins in mammals: insights into their biological function

7 April 2017

1 reference

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Adjusting batch effects in microarray expression data using empirical Bayes methods

7 April 2017

1 reference

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Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740465

Rational siRNA design for RNA interference

7 April 2017

1 reference

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The NAD World: a new systemic regulatory network for metabolism and aging--Sirt1, systemic NAD biosynthesis, and their importance

7 April 2017

1 reference

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Nampt: linking NAD biology, metabolism and cancer

27 September 2017

1 reference

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Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase.

27 September 2017

1 reference

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Nicotinamide phosphoribosyl transferase/pre-B cell colony-enhancing factor/visfatin is required for lymphocyte development and cellular resistance to genotoxic stress

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740465

Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt

27 September 2017

1 reference

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Transcriptional targets of sirtuins in the coordination of mammalian physiology

27 September 2017

1 reference

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Transcriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulation

27 September 2017

1 reference

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NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740465

Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes

27 September 2017

1 reference

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Characterization of NAD uptake in mammalian cells

27 September 2017

1 reference

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NAD+ and vitamin B3: from metabolism to therapies

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740465

The haemostatic role of tissue factor pathway inhibitor.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740465

NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740465

Genomic analyses of transcription factor binding, histone acetylation, and gene expression reveal mechanistically distinct classes of estrogen-regulated promoters

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740465

Suppressor of cytokine signaling (SOCS) 2, a protein with multiple functions.

27 September 2017

1 reference

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Tracking in the Wlds--the hunting of the SIRT and the luring of the Draper

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740465

The biochemistry of sirtuins.

27 September 2017

1 reference

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SIRT1 and endocrine signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740465

NAD(+) and axon degeneration revisited: Nmnat1 cannot substitute for Wld(S) to delay Wallerian degeneration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740465

Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740465

Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor

27 September 2017

1 reference

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Growth hormone and SOCS2 regulation of neuronal differentiation: possible role in mental function

27 September 2017

1 reference

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The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells

27 September 2017

1 reference

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Small molecule regulation of Sir2 protein deacetylases

27 September 2017

1 reference

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Pre-B-cell colony-enhancing factor regulates NAD+-dependent protein deacetylase activity and promotes vascular smooth muscle cell maturation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740465

Recent progress in spinocerebellar ataxia type-10 (SCA10).

27 September 2017

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NPY and Y receptors: lessons from transgenic and knockout models

27 September 2017

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The new life of a centenarian: signalling functions of NAD(P).

27 September 2017

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Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis

27 September 2017

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Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

27 September 2017

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A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse

27 September 2017

1 reference

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Sir2 links chromatin silencing, metabolism, and aging

27 September 2017

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Complexes of sequential metabolic enzymes

27 September 2017

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Immunohistochemical localization of tissue factor pathway inhibitor-1 (TFPI-1), a Kunitz proteinase inhibitor, in Alzheimer's disease.

27 September 2017

1 reference

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The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons

30 May 2018

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Wlds protection distinguishes axon degeneration following injury from naturally occurring developmental pruning

21 January 2018

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N-acetyltransferase ARD1-NAT1 regulates neuronal dendritic development.

21 January 2018

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NELL2 promotes motor and sensory neuron differentiation and stimulates mitogenesis in DRG in vivo.

21 January 2018

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Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells

21 January 2018

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Extension of human cell lifespan by nicotinamide phosphoribosyltransferase

29 November 2018

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