The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells (Q24314985)

negative regulation of T cell activation

GOA release 2020-03-11

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T-cell immunoreceptor with Ig and ITIM domains

GOA release 2020-03-11

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GOA release 2020-03-11

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1 reference

Xin Yu

1

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Kristin Harden

2

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Lino C Gonzalez

3

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Michelle Francesco

4

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Eugene Chiang

5

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Bryan Irving

6

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Irene Tom

7

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Sinisa Ivelja

8

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Canio J Refino

9

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Hilary Clark

10

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Dan Eaton

11

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Jane L Grogan

Characterization of Dendritic Cells that Induce Tolerance and T Regulatory 1 Cell Differentiation In Vivo

12

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language of work or name

English

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publication date

January 2009

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published in

Nature Immunology

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volume

10

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issue

1

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page(s)

48-57

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cites work

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12 December 2020

Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule

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12 December 2020

Dendritic cells: specialized and regulated antigen processing machines

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12 December 2020

CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.

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12 December 2020

Modulation of tryptophan catabolism by regulatory T cells.

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12 December 2020

DNAM-1 and PVR regulate monocyte migration through endothelial junctions

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12 December 2020

Dendritic Cell Function in Vivo during the Steady State: A Role in Peripheral Tolerance

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12 December 2020

CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells.

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12 December 2020

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

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12 December 2020

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

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12 December 2020

The role of NK cell recognition of nectin and nectin-like proteins in tumor immunosurveillance

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12 December 2020

DC-SIGN ligation on dendritic cells results in ERK and PI3K activation and modulates cytokine production.

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12 December 2020

Regulatory T cells and intestinal homeostasis

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12 December 2020

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

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12 December 2020

Biology and pathology of nectins and nectin-like molecules

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12 December 2020

Immunoreceptor tyrosine-based inhibitory motif of the IL-4 receptor associates with SH2-containing phosphatases and regulates IL-4-induced proliferation

1 reference

12 December 2020

Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos.

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12 December 2020

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment

1 reference

12 December 2020

A novel phosphotyrosine motif with a critical amino acid at position -2 for the SH2 domain-mediated activation of the tyrosine phosphatase SHP-1

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12 December 2020

Development and function of CD25+CD4+ regulatory T cells

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12 December 2020

Tage4/Nectin-like molecule-5 heterophilically trans-interacts with cell adhesion molecule Nectin-3 and enhances cell migration

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12 December 2020

Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation

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12 December 2020

Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112)

1 reference

12 December 2020

Neuropilin-1: a surface marker of regulatory T cells

1 reference

12 December 2020

High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

1 reference

12 December 2020

In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation

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12 December 2020

CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function

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12 December 2020

The B7 family revisited

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12 December 2020

Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction

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12 December 2020

Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation

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12 December 2020

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

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12 December 2020

Control of regulatory T cell development by the transcription factor Foxp3

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12 December 2020

Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data.

1 reference

12 December 2020

A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator

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12 December 2020

Complexes of poliovirus serotypes with their common cellular receptor, CD155

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12 December 2020

CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions

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12 December 2020

Receptor binding and biological activity of mammalian expressed sensory and motor neuron-derived factor (SMDF)

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12 December 2020

Nerve growth factor: structure and function

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12 December 2020

Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155)

1 reference

12 December 2020

Dendritic cells partially abrogate the regulatory activity of CD4+CD25+ T cells present in the human peripheral blood

1 reference

12 December 2020

Nectin-3, a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities

1 reference

12 December 2020

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

1 reference

12 December 2020

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

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12 December 2020

Cross-linking of the mannose receptor on monocyte-derived dendritic cells activates an anti-inflammatory immunosuppressive program

1 reference

12 December 2020

DC-SIGN: escape mechanism for pathogens

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12 December 2020

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

1 reference

12 December 2020

Suppression of interleukin-12 production through endogenously secreted interleukin-10 in activated dendritic cells: involvement of activation of extracellular signal-regulated protein kinase.

1 reference

12 December 2020