Ribonuclease activity and RNA binding of recombinant human Dicer (Q24315047)

ribonuclease III activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

6

Olof Rådmark

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author name string

Patrick Provost

1

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David Dishart

2

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Johanne Doucet

3

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David Frendewey

4

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Bengt Samuelsson

Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

5

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language of work or name

English

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publication date

1 November 2002

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published in

The EMBO Journal

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volume

21

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page(s)

5864-74

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issue

21

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cites work

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Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage

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Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

19 March 2017

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Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

19 March 2017

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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Role for a bidentate ribonuclease in the initiation step of RNA interference

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Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

19 March 2017

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

19 March 2017

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Alternative 3'-end processing of U5 snRNA by RNase III.

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RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

7 April 2017

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ATP requirements and small interfering RNA structure in the RNA interference pathway

7 April 2017

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A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans

7 April 2017

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RNase III cleaves eukaryotic preribosomal RNA at a U3 snoRNP-dependent site

7 April 2017

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RNAi: nature abhors a double-strand

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27 September 2017

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Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines.

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Pac1p, an RNase III homolog, is required for formation of the 3' end of U2 snRNA in Schizosaccharomyces pombe

27 September 2017

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27 September 2017

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Purification and characterization of the Pac1 ribonuclease of Schizosaccharomyces pombe

27 September 2017

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Ribonuclease III cleavage of a bacteriophage T7 processing signal. Divalent cation specificity, and specific anion effects

27 September 2017

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5-Lipoxygenase is located in the euchromatin of the nucleus in resting human alveolar macrophages and translocates to the nuclear envelope upon cell activation

27 September 2017

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Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

27 September 2017

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A gene from S. pombe with homology to E. coli RNAse III blocks conjugation and sporulation when overexpressed in wild type cells

27 September 2017

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S. pombe pac1+, whose overexpression inhibits sexual development, encodes a ribonuclease III-like RNase

27 September 2017

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Quelling: transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences

27 September 2017

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RNA as a target and an initiator of post-transcriptional gene silencing in transgenic plants

27 September 2017

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Substrate structure requirements of the Pac1 ribonuclease from Schizosaccharmyces pombe

27 September 2017

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Rescue of the fission yeast snRNA synthesis mutant snm1 by overexpression of the double-strand-specific Pac1 ribonuclease

30 May 2018

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Purification and properties of ribonuclease III from Escherichia coli.

30 May 2018

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Intrinsic double-stranded-RNA processing activity of Escherichia coli ribonuclease III lacking the dsRNA-binding domain

30 May 2018

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Pac1 ribonuclease of Schizosaccharomyces pombe

29 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/12411504