E2A basic-helix-loop-helix transcription factors are negatively regulated by serum growth factors and by the Id3 protein (Q24316427)

An immediate early human gene encodes an Id-like helix-loop-helix protein and is regulated by protein kinase C activation in diverse cell types

GOA release 2020-03-11

author name string

D A Loveys

series ordinal

1

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M B Streiff

series ordinal

2

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G J Kato

series ordinal

3

0 references

language of work or name

English

0 references

publication date

15 July 1996

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published in

Nucleic Acids Research

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volume

24

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page(s)

2813-20

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issue

14

0 references

cites work

1 reference

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Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells

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The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif

19 March 2017

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Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

19 March 2017

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A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

19 March 2017

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Sequence of the cDNA encoding ITF-2, a positive-acting transcription factor

19 March 2017

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The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein

19 March 2017

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Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity

19 March 2017

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Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif

19 March 2017

1 reference

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Mutually exclusive expression of a helix-loop-helix gene and N-myc in human neuroblastomas and in normal development

19 March 2017

1 reference

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Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia

19 March 2017

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HEB, a Helix-Loop-Helix Protein Related to E2A and ITF2 That Can Modulate the DNA-Binding Ability of Myogenic Regulatory Factors

19 March 2017

1 reference

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Consequences of heteromeric interactions among helix-loop-helix proteins

19 March 2017

1 reference

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Detection and modulation in vivo of helix-loop-helix protein-protein interactions

19 March 2017

1 reference

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19 March 2017

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Posttranscriptional regulation of Id1 activity in cardiac muscle. Alternative splicing of novel Id1 transcript permits homodimerization

19 March 2017

1 reference

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Structure and function of helix-loop-helix proteins

19 March 2017

1 reference

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Crystal structure of transcription factor E47: E-box recognition by a basic region helix-loop-helix dimer

19 March 2017

1 reference

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Activation of helix-loop-helix proteins Id1, Id2 and Id3 during neural differentiation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Structural organisation and chromosomal mapping of the human Id-3 gene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

The protein Id: a negative regulator of helix-loop-helix DNA binding proteins

19 March 2017

1 reference

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19 March 2017

1 reference

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Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins

19 March 2017

1 reference

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Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Murine helix-loop-helix transcriptional activator proteins binding to the E-box motif of the Akv murine leukemia virus enhancer identified by cDNA cloning

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

The MyoD family and myogenesis: redundancy, networks, and thresholds

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons

7 April 2017

1 reference

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A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Preferred sequences for DNA recognition by the TAL1 helix-loop-helix proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

HLH proteins, fly neurogenesis, and vertebrate myogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Multiple oligomeric states regulate the DNA binding of helix-loop-helix peptides

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

The loop region of the helix-loop-helix protein Id1 is critical for its dominant negative activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Neuronal expression of regulatory helix-loop-helix factor Id2 gene in mouse

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Id proteins control growth induction in mammalian cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

The helix-loop-helix protein Id inhibits differentiation of murine erythroleukemia cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Regulation of G1 progression by E2A and Id helix-loop-helix proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Class A basic helix-loop-helix transcription factors in early stages of chick neural tube development: evidence for functional redundancy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region

27 September 2017

1 reference

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MyoD binds cooperatively to two sites in a target enhancer sequence: occupancy of two sites is required for activation

27 September 2017

1 reference

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MyoD induces growth arrest independent of differentiation in normal and transformed cells

27 September 2017

1 reference

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A cDNA from a mouse pancreatic beta cell encoding a putative transcription factor of the insulin gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins

27 September 2017

1 reference

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Oncogenic conversion by regulatory changes in transcription factors

27 September 2017

1 reference

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Molecular themes in oncogenesis

27 September 2017

1 reference

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Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Repression of immunoglobulin enhancers by the helix-loop-helix protein Id: implications for B-lymphoid-cell development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Functional characterization of the developmentally controlled immunoglobulin kappa 3' enhancer: regulation by Id, a repressor of helix-loop-helix transcription factors

27 September 2017

1 reference

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Primary response genes induced by growth factors and tumor promoters

27 September 2017

1 reference

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An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not in E12 heterodimers

27 September 2017

1 reference

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Max: functional domains and interaction with c-Myc

27 September 2017

1 reference

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Myocardial activation of the human cardiac alpha-actin promoter by helix-loop-helix proteins

27 September 2017

1 reference

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Activation of muscle-specific transcription by myogenic helix-loop-helix proteins

27 September 2017

1 reference

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DNA binding and transcriptional regulatory activity of mammalian achaete-scute homologous (MASH) proteins revealed by interaction with a muscle-specific enhancer

27 September 2017

1 reference

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Cell proliferation inhibited by MyoD1 independently of myogenic differentiation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Expression of ID, a negative regulator of helix-loop-helix DNA binding proteins, is down-regulated at confluence and enhanced by dexamethasone in a mouse osteoblastic cell line, MC3T3E1

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line

30 May 2018

1 reference

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Inhibition of myeloid differentiation by the helix-loop-helix protein Id

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=145994

The gene for the helix-loop-helix protein, Id, is specifically expressed in neural precursors

29 November 2018

1 reference

12 December 2020

Id expression during mouse development: a role in morphogenesis

1 reference

12 December 2020

Expression of the helix-loop-helix factor Id during mouse embryonic development

1 reference

12 December 2020

Expression of helix-loop-helix factor Id-1 is dependent on the hepatocyte proliferation and differentiation status in rat liver and in primary culture

1 reference

12 December 2020

Constitutive expression of the Id1 gene impairs mouse B cell development

1 reference

12 December 2020