A human ubiquitin conjugating enzyme, L-UBC, maps in the Alzheimer's disease locus on chromosome 14q24.3 (Q24317155)

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14 October 2019

title

A human ubiquitin conjugating enzyme, L-UBC, maps in the Alzheimer's disease locus on chromosome 14q24.3. (English)

1 reference

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14 October 2019

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Ubiquitin conjugating enzyme E2 L3

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GOA release 2020-03-11

enzyme binding

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GOA release 2020-03-11

author

Nicholas Lench

8

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14 October 2019

author name string

P A Robinson

1

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14 October 2019

J P Leek

2

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14 October 2019

J Thompson

3

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14 October 2019

I M Carr

4

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14 October 2019

A Bailey

5

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14 October 2019

T P Moynihan

6

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14 October 2019

P L Coletta

7

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14 October 2019

A F Markham

9

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14 October 2019

language of work or name

English

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publication date

1 October 1995

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14 October 2019

number of pages

7

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inferred from page(s)

published in

Mammalian Genome

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14 October 2019

volume

6

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14 October 2019

issue

10

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14 October 2019

page(s)

725-731

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The ubc-2 gene of Caenorhabditis elegans encodes a ubiquitin-conjugating enzyme involved in selective protein degradation

14 October 2019

cites work

1 reference

Crossref

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Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor.

21 January 2018

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Ubiquitin is conjugated with amino-terminally processed tau in paired helical filaments

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Method for sequential staining of GTL-banded metaphases with fluorescent-labeled chromosome-specific paint probes

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Use of whole cosmid cloned genomic sequences for chromosomal localization by non-radioactive in situ hybridization

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Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31

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A candidate spermatogenesis gene on the mouse Y chromosome is homologous to ubiquitin-activating enzyme E1

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12 December 2020

Reconstitution of p53-ubiquitinylation reactions from purified components: the role of human ubiquitin-conjugating enzyme UBC4 and E6-associated protein (E6AP)

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Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins

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12 December 2020

The Drosophila bendless gene encodes a neural protein related to ubiquitin-conjugating enzymes

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12 December 2020

Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway

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Alzheimer's disease: the amyloid cascade hypothesis

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A simple method for displaying the hydropathic character of a protein

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Drosophila UbcD1 encodes a highly conserved ubiquitin-conjugating enzyme involved in selective protein degradation

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A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

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Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

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Binding sites of ubiquitin-protein ligase. Binding of ubiquitin-protein conjugates and of ubiquitin-carrier protein

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The ubiquitin-mediated proteolytic pathway: mechanisms of recognition of the proteolytic substrate and involvement in the degradation of native cellular proteins.

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Evidence that production and release of amyloid beta-protein involves the endocytic pathway

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Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53

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Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins

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Cell surface control of the multiubiquitination and deubiquitination of high-affinity immunoglobulin E receptors

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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The ubiquitin-proteasome proteolytic pathway

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Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway.

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Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeast

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Differential expression of protease inhibitor and small proline-rich protein genes between normal human oral tissue and odontogenic keratocysts

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Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodie

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12 December 2020

Tau as a marker for Alzheimer's disease

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Genetic analysis of the ubiquitin system

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The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene

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The ubiquitin system for protein degradation

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Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains

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Tau protein, aluminium, and Alzheimer's disease

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12 December 2020

Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14.

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12 December 2020

A human ubiquitin-conjugating enzyme homologous to yeast UBC8

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12 December 2020

Degradation of the tumor suppressor protein p53 by the ubiquitin-mediated proteolytic system requires a novel species of ubiquitin-carrier protein, E2

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12 December 2020

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

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12 December 2020

Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

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12 December 2020

A gene in the chromosomal region 3p21 with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme

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12 December 2020

A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal to the alpha 1-antichymotrypsin gene.

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12 December 2020

Alzheimer's-disease-like changes in tau protein processing: association with aluminium accumulation in brains of renal dialysis patients

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12 December 2020

The Pichia pastoris PAS4 gene encodes a ubiquitin-conjugating enzyme required for peroxisome assembly.

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12 December 2020

Proteolysis, proteasomes and antigen presentation

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12 December 2020

Ubiquitin-conjugating enzymes: novel regulators of eukaryotic cells

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12 December 2020

The ubiquitin-conjugation system

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12 December 2020

Purification and characterization of a novel species of ubiquitin-carrier protein, E2, that is involved in degradation of non-"N-end rule" protein substrates

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12 December 2020

The mechanism of ubiquitin activating enzyme. A kinetic and equilibrium analysis

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12 December 2020

Mapping of a gene predisposing to early-onset Alzheimer's disease to chromosome 14q24.3

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12 December 2020

Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14

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12 December 2020

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

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12 December 2020

Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1.

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12 December 2020

Ubiquitin is a component of paired helical filaments in Alzheimer's disease.

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12 December 2020