Direct involvement of the ubiquitin-conjugating enzyme Ubc9/Hus5 in the degradation of IkappaBalpha (Q24317303)

Ubiquitin-conjugating enzyme E2I

GOA release 2020-03-11

1 reference

Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

K Tashiro

1

0 references

M P Pando

2

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Y Kanegae

3

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P M Wamsley

4

0 references

S Inoue

5

0 references

I M Verma

Proceedings of the National Academy of Sciences of the United States of America

6

0 references

language of work or name

English

0 references

publication date

22 July 1997

0 references

published in

0 references

volume

94

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issue

15

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page(s)

7862-7

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cites work

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A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

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Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

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Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha

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Mammalian Ras interacts directly with the serine/threonine kinase Raf

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Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

19 March 2017

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Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

19 March 2017

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Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway

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7 April 2017

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The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

7 April 2017

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Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha

27 September 2017

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27 September 2017

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In vivo stimulation of I kappa B phosphorylation is not sufficient to activate NF-kappa B

27 September 2017

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Inducible degradation of I kappa B alpha in vitro and in vivo requires the acidic C-terminal domain of the protein

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation

27 September 2017

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27 September 2017

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The Schizosaccharomyces pombe hus5 gene encodes a ubiquitin conjugating enzyme required for normal mitosis.

30 May 2018

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Role of IkappaBalpha ubiquitination in signal-induced activation of NFkappaB in vivo

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I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

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PubMed

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Characterization of a dominant negative mutant of the cell cycle ubiquitin-conjugating enzyme Cdc34

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