Pyruvate dehydrogenase kinase-4 structures reveal a metastable open conformation fostering robust core-free basal activity (Q24317423)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18658136%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

title

Pyruvate dehydrogenase kinase-4 structures reveal a metastable open conformation fostering robust core-free basal activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18658136%20AND%20SRC:MED&resulttype=core&format=json

Pyruvate dehydrogenase kinase 4

11 January 2020

main subject

cell biology

0 references

1 reference

GOA release 2020-03-11

ATP binding

1 reference

GOA release 2020-03-11

author

Richard M Wynn

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18658136%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

author name string

Masato Kato

2

1 reference

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11 January 2020

Jacinta L Chuang

3

1 reference

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11 January 2020

Shih-Chia Tso

4

1 reference

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11 January 2020

Jun Li

5

1 reference

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11 January 2020

David T Chuang

6

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11 January 2020

language of work or name

English

0 references

publication date

24 July 2008

1 reference

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Journal of Biological Chemistry

11 January 2020

published in

1 reference

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11 January 2020

volume

283

1 reference

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11 January 2020

issue

37

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11 January 2020

page(s)

25305-25315

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Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol

11 January 2020

cites work

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Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex

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19 March 2017

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19 March 2017

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Pyruvate dehydrogenase kinase isoform 2 activity stimulated by speeding up the rate of dissociation of ADP

19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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30 May 2018

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30 May 2018

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30 May 2018

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30 May 2018

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30 May 2018

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30 May 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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29 November 2018

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Identifiers

DOI

10.1074/JBC.M802249200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18658136%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18658136%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference