Nucleolin is a receptor that mediates antiangiogenic and antitumor activity of endostatin (Q24317515)

2

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Hao Zhou

3

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Xiaomin Song

4

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Shaopeng Yuan

5

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Yan Fu

6

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Yongzhang Luo

The self-cleaving activity of nucleolin determines its molecular dynamics in relation to cell proliferation

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language of work or name

English

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publication date

15 October 2007

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published in

Blood

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volume

110

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issue

8

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page(s)

2899-906

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cites work

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Major nucleolar proteins shuttle between nucleus and cytoplasm

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Detection and characterization of an acid-induced folding intermediate of endostatin

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Antiangiogenesis in cancer therapy--endostatin and its mechanisms of action

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Human endostatin-derived synthetic peptides possess potent antiangiogenic properties in vitro and in vivo

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Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').

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7 January 2021

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

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Cell surface glypicans are low-affinity endostatin receptors

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Endostatin's antiangiogenic signaling network

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7 January 2021

Acid-induced unfolding mechanism of recombinant human endostatin

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Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance.

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Tumor angiogenesis: therapeutic implications

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Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors

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Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins

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7 January 2021

A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

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Comparison of nucleolar proteins of normal rat liver and Novikoff hepatoma ascites cells by two-dimensional polyacrylamide gel electrophoresis

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Basic fibroblast growth factor enters the nucleolus and stimulates the transcription of ribosomal genes in ABAE cells undergoing G0----G1 transition

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Nucleolin, the major nucleolar protein of growing eukaryotic cells: an unusual protein structure revealed by the nucleotide sequence

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7 January 2021

Interaction of endostatin with integrins implicated in angiogenesis

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7 January 2021

Fibroblast growth factor-2 binds to the regulatory beta subunit of CK2 and directly stimulates CK2 activity toward nucleolin

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7 January 2021

Identification of V3 loop-binding proteins as potential receptors implicated in the binding of HIV particles to CD4(+) cells.

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Endostatin induces endothelial cell apoptosis

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7 January 2021

Endostatin binds tropomyosin. A potential modulator of the antitumor activity of endostatin.

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Contributions of disulfide bonds in a nested pattern to the structure, stability, and biological functions of endostatin

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Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels

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7 January 2021

Structure, function and tissue forms of the C-terminal globular domain of collagen XVIII containing the angiogenesis inhibitor endostatin

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7 January 2021

Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding

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7 January 2021

Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin

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7 January 2021

Role of heparan sulfate domain organization in endostatin inhibition of endothelial cell function

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7 January 2021

What Is the Evidence That Tumors Are Angiogenesis Dependent?

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Characterization of a 100-kilodalton binding protein for the six serotypes of coxsackie B viruses

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7 January 2021

Nuclear targeting by the growth factor midkine

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7 January 2021

A 27-amino-acid synthetic peptide corresponding to the NH2-terminal zinc-binding domain of endostatin is responsible for its antitumor activity

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7 January 2021

The angiogenic function of nucleolin is mediated by vascular endothelial growth factor and nonmuscle myosin

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7 January 2021

Endothelial progenitor cells from infantile hemangioma and umbilical cord blood display unique cellular responses to endostatin.

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7 January 2021

Phase I clinical trial of recombinant human endostatin administered as a short intravenous infusion repeated daily.

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7 January 2021

Phase I study of recombinant human endostatin in patients with advanced solid tumors

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7 January 2021

Depletion of CXCR2 inhibits tumor growth and angiogenesis in a murine model of lung cancer

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7 January 2021