Regulation of planar cell polarity by Smurf ubiquitin ligases (Q24317525)

Par-6 family cell polarity regulator alpha

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Rohit Bose

2

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Liang N Zhang

object named as

Liang Zhang

4

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Jeffrey L. Wrana

11

object named as

Jeffrey L Wrana

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author name string

Masahiro Narimatsu

1

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Melanie Pye

3

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Bryan Miller

5

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Peter Ching

6

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Rui Sakuma

7

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Valbona Luga

8

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Luba Roncari

9

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Liliana Attisano

Planar cell polarity in the inner ear: how do hair cells acquire their oriented structure?

10

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language of work or name

English

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publication date

17 April 2009

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published in

Cell

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volume

137

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issue

2

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page(s)

295-307

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cites work

1 reference

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Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

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Planar polarity and tissue morphogenesis

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Ascidian prickle regulates both mediolateral and anterior-posterior cell polarity of notochord cells

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Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway

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XGAP, an ArfGAP, is required for polarized localization of PAR proteins and cell polarity in Xenopus gastrulation

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Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development

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Frizzled-Dishevelled signaling specificity outcome can be modulated by Diego in Drosophila

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Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain

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Wnt5a functions in planar cell polarity regulation in mice

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Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

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Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling

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Abnormalities of floor plate, notochord and somite differentiation in the loop-tail (Lp) mouse: a model of severe neural tube defects.

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Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse

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The asymmetric subcellular localisation of components of the planar polarity pathway

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The DSmurf ubiquitin-protein ligase restricts BMP signaling spatially and temporally during Drosophila embryogenesis.

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Convergent extension: the molecular control of polarized cell movement during embryonic development

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Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail

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Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

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Planar cell polarity signalling couples cell division and morphogenesis during neurulation.

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Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding

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Dishevelled promotes axon differentiation by regulating atypical protein kinase C.

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Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway

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The genetic basis of mammalian neurulation.

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Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility

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Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family

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Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility

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Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity

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Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification

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Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

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Shaping the vertebrate body plan by polarized embryonic cell movements

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Regulation of cell polarity and protrusion formation by targeting RhoA for degradation

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Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

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High-throughput mapping of a dynamic signaling network in mammalian cells

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Strabismus is asymmetrically localised and binds to Prickle and Dishevelled during Drosophila planar polarity patterning

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Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling.

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Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes.

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Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation

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Tissue/planar cell polarity in vertebrates: new insights and new questions

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Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals

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The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells

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Asymmetric distribution of prickle-like 2 reveals an early underlying polarization of vestibular sensory epithelia in the inner ear

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Ubiquitin-dependent regulation of TGFbeta signaling in cancer

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