SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans (Q24317576)

Ras protein signal transduction

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Leucine-rich repeat protein soc-2 CELE_AC7.2

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Ras protein let-60 CELE_ZK792.6

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Raf homolog serine/threonine-protein kinase CELE_Y73B6A.5

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Differential structural requirements for interaction of Ras protein with its distinct downstream effectors.

author name string

D S Sieburth

series ordinal

1

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Q Sun

series ordinal

2

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M Han

series ordinal

3

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language of work or name

English

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publication date

10 July 1998

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published in

Cell

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volume

94

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issue

1

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page(s)

119-30

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cites work

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Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction

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The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway.

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Isolation of rsp-1, a novel cDNA capable of suppressing v-Ras transformation

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Raf functions downstream of Ras1 in the Sevenless signal transduction pathway

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A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans.

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Mutations of the adenylyl cyclase gene that block RAS function in Saccharomyces cerevisiae

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The Caenorhabditis elegans SH2 domain-containing protein tyrosine phosphatase PTP-2 participates in signal transduction during oogenesis and vulval development

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7 January 2021

let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein

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C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation.

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Amino acid sequence of the ribonuclease inhibitor from porcine liver reveals the presence of leucine-rich repeats

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7 January 2021

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

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Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

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Signal transduction from multiple Ras effectors

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Alterations in cell lineage following laser ablation of cells in the somatic gonad of Caenorhabditis elegans

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Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats

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The leucine-rich repeat: a versatile binding motif

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Vulval development in Caenorhabditis elegans

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The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans

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Differential expression of the ras gene family in mice

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Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

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The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction

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7 January 2021

Control and integration of cell signaling pathways during C. elegans vulval development

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Leucine-rich repeats and carboxyl terminus are required for interaction of yeast adenylate cyclase with RAS proteins

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7 January 2021

KSR, a novel protein kinase required for RAS signal transduction

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The murine N-ras gene is not essential for growth and development

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The Ras signaling pathway in Drosophila

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Multiple Ras functions can contribute to mammalian cell transformation

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Suppression of activated Let-60 ras protein defines a role of Caenorhabditis elegans Sur-1 MAP kinase in vulval differentiation

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Ras is required for a limited number of cell fates and not for general proliferation in Caenorhabditis elegans

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Ras-Raf complexes in vitro

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