Structure-based design of 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinases 1 and 2 (Q24318338)

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7 November 2019

title

Structure-based design of 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinases 1 and 2 (English)

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7 November 2019

1

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7 November 2019

Nicola Curtin

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7 November 2019

Martin Noble

13

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7 November 2019

author name string

Johanne Bentley

2

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7 November 2019

F Thomas Boyle

3

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7 November 2019

A Hilary Calvert

4

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7 November 2019

Yuzhu Cheng

5

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7 November 2019

Jane A Endicott

7

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7 November 2019

Bernard T Golding

8

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7 November 2019

Ian R Hardcastle

9

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7 November 2019

Philip Jewsbury

10

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7 November 2019

Veronique Mesguiche

11

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7 November 2019

David R Newell

12

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Rachel J Parsons

14

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David J Pratt

15

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Lan Z Wang

16

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7 November 2019

Roger J Griffin

17

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7 November 2019

language of work or name

English

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publication date

1 September 2003

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Bioorganic & Medicinal Chemistry Letters

7 November 2019

published in

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7 November 2019

volume

13

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7 November 2019

issue

18

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7 November 2019

page(s)

3079-3082

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7 November 2019

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Preclinical and clinical development of cyclin-dependent kinase modulators

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Roscovitine and other purines as kinase inhibitors. From starfish oocytes to clinical trials

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Complexities in the development of cyclin-dependent kinase inhibitor drugs

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7 January 2021

Pharmacological inhibitors of cyclin-dependent kinases

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7 January 2021

Designing inhibitors of cyclin-dependent kinases

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7 January 2021

Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles

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Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives

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7 January 2021

4-Alkoxy-2,6-diaminopyrimidine derivatives: inhibitors of cyclin dependent kinases 1 and 2.

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Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor

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The United Kingdom Chemical Database Service

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7 January 2021

10.1016/S0960-894X(03)00651-6

Identifiers

DOI

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7 November 2019

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