CIP2A inhibits PP2A in human malignancies (Q24319683)

20

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Johanna Ivaska

object named as

Johanna Ivaska

9

0 references

Janet Pope

1 reference

ORCID Public Data File 2021

author name string

Melissa R Junttila

1

0 references

Pietri Puustinen

2

0 references

Minna Niemelä

3

0 references

Raija Ahola

4

0 references

Hugh Arnold

5

0 references

Trine Böttzauw

6

0 references

Risto Ala-aho

7

0 references

Christina Nielsen

8

0 references

Yoichi Taya

10

0 references

Shi-Long Lu

11

0 references

Shujun Lin

12

0 references

Edward K L Chan

13

0 references

Xiao-Jing Wang

14

0 references

Reidar Grènman

15

0 references

Juergen Kast

16

0 references

Tuula Kallunki

17

0 references

Rosalie Sears

18

0 references

Veli-Matti Kähäri

Species- and cell type-specific requirements for cellular transformation

19

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language of work or name

English

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publication date

13 July 2007

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published in

Cell

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volume

130

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issue

1

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page(s)

51-62

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cites work

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The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein

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Structure of the protein phosphatase 2A holoenzyme

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PP2A: the expected tumor suppressor

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Cyclin G recruits PP2A to dephosphorylate Mdm2

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Identification of specific PP2A complexes involved in human cell transformation

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Creation of human tumour cells with defined genetic elements

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Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme

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A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

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c-MYC: more than just a matter of life and death

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JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways

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Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms

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Cloning and characterization of a novel 90 kDa 'companion' auto-antigen of p62 overexpressed in cancer.

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Involvement of PP2A in viral and cellular transformation

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Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

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Role for PP2A in ARF signaling to p53.

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Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha

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A conserved pathway that controls c-Myc protein stability through opposing phosphorylation events occurs in yeast

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Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

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c-Myc promotes differentiation of human epidermal stem cells

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Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma

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c-Myc and epidermal stem cell fate determination

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Alterations of the PPP2R1B gene in human lung and colon cancer

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Enumeration of the simian virus 40 early region elements necessary for human cell transformation

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Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation

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Genetic and epigenetic alterations in colon cancer

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Signaling and transcriptional changes critical for transformation of human cells by simian virus 40 small tumor antigen or protein phosphatase 2A B56gamma knockdown

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Cancer-associated PP2A Aalpha subunits induce functional haploinsufficiency and tumorigenicity

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