Karyopherin beta2 mediates nuclear import of a mRNA binding protein (Q24319692)

protein import into nucleus

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Günter Blobel

4

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author name string

N Bonifaci

1

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J Moroianu

2

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A Radu

Proceedings of the National Academy of Sciences of the United States of America

3

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language of work or name

English

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publication date

13 May 1997

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published in

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volume

94

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issue

10

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page(s)

5055-60

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cites work

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Previously identified protein of uncertain function is karyopherin alpha and together with karyopherin beta docks import substrate at nuclear pore complexes

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The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

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A karyophilic protein forms a stable complex with cytoplasmic components prior to nuclear pore binding

27 September 2017

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The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factors

30 May 2018

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