AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC (Q24319706)

PYD and CARD domain containing

1 reference

NLR family pyrin domain containing 3

1 reference

negative regulation of interferon-beta production

1 reference

PYD and CARD domain containing

1 reference

Absent in melanoma 2

1 reference

1 reference

1

0 references

Eicke Latz

7

0 references

Gabor L Horvath

Gabor Horvath

5

0 references

Daniel R Caffrey

6

Daniel R Caffrey

0 references

Katherine A. Fitzgerald

8

Katherine A Fitzgerald

0 references

Andrea Ablasser

2

Andrea Ablasser

0 references

author name string

Marie Charrel-Dennis

3

0 references

Franz Bauernfeind

describes a project that uses

4

0 references

language of work or name

English

0 references

publication date

26 March 2009

0 references

published in

Nature

0 references

volume

458

0 references

page(s)

514-8

0 references

issue

7237

0 references

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2726264/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

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PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B

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Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

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The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

19 March 2017

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Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

7 April 2017

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Type I interferon signaling is required for activation of the inflammasome during Francisella infection

27 September 2017

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27 September 2017

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Intracellular pattern recognition receptors in the host response

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Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

27 September 2017

1 reference

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

1 reference

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29 November 2018

1 reference

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29 November 2018

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Antitumor activity of IFIX, a novel interferon-inducible HIN-200 gene, in breast cancer

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1 reference

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Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1beta, IL-6, IL-8, IL-10 and TNF-alpha from normal human mononuclear cells involving in the lupus pathogenesis

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1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19158675

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Toll-like receptor-dependent and -independent viperin gene expression and counter-regulation by PRDI-binding factor-1/BLIMP1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19158675

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE07725

1 reference

Dimensions Publication ID

399054

1023911990

0 references

399054

1 reference

1 reference

1 reference