Biosynthesis, distinct post-translational modifications, and functional characterization of lymphoma proprotein convertase (Q24320002)

GOA release 2020-03-11

author name string

J W van de Loo

1

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J W Creemers

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N A Bright

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B D Young

4

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A J Roebroek

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W J Van de Ven

Journal of Biological Chemistry

6

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language of work or name

English

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publication date

24 October 1997

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published in

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volume

272

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issue

43

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page(s)

27116-23

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cites work

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Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes

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A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains

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PC8 [corrected], a new member of the convertase family

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Identification and analysis of the gene encoding human PC2, a prohormone convertase expressed in neuroendocrine tissues

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cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases

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Oligomerization of a trans-Golgi/trans-Golgi network retained protein occurs in the Golgi complex and may be part of its retention

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A casein kinase II phosphorylation site in the cytoplasmic domain of the cation-dependent mannose 6-phosphate receptor determines the high affinity interaction of the AP-1 Golgi assembly proteins with membranes

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Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines

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Endoprotease activities other than furin and PACE4 with a role in processing of HIV-I gp160 glycoproteins in CHO-K1 cells

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Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat

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Immunolocalization of Kex2 protease identifies a putative late Golgi compartment in the yeast Saccharomyces cerevisiae

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Posttranslational processing of the prohormone-cleaving Kex2 protease in the Saccharomyces cerevisiae secretory pathway

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The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system.

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A novel adaptor-related protein complex

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SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.

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Development and Characterization of a Panel of Monoclonal Antibodies Against the Novel Subtilisin-Like Proprotein Processing Enzyme Furin

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Mutation of a tyrosine localization signal in the cytosolic tail of yeast Kex2 protease disrupts Golgi retention and results in default transport to the vacuole

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Sequence requirements for endoproteolytic processing of precursor proteins by furin: transfection and in vitro experiments.

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Intracellular targeting and structural conservation of a prohormone-processing endoprotease

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