The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8 (Q24320007)

signaling receptor activity

GOA release 2020-03-11

1 reference

hereditary renal cell carcinoma

GOA release 2020-03-11

1 reference

1 reference

R M Gemmill

1

0 references

J D West

2

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F Boldog

3

0 references

N Tanaka

4

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L J Robinson

5

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D I Smith

6

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F Li

7

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H A Drabkin

Proceedings of the National Academy of Sciences of the United States of America

8

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language of work or name

English

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publication date

4 August 1998

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published in

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volume

95

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issue

16

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page(s)

9572-7

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The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers

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Aberrant splicing of the TSG101 and FHIT genes occurs frequently in multiple malignancies and in normal tissues and mimics alterations previously described in tumours

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Normal FHIT transcripts in renal cell cancer- and lung cancer-derived cell lines, including a cell line with a homozygous deletion in the FRA3B region

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Variable FHIT transcripts in non-neoplastic tissues

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Involvement of multiple loci on chromosome 3 in renal cell cancer development

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27 September 2017

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Integrated YAC contig containing the 3p14.2 hereditary renal carcinoma 3;8 translocation breakpoint and the fragile site FRA3B.

27 September 2017

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27 September 2017

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A 1.5-megabase restriction map surrounding MYC does not include the translocation breakpoint in familial renal cell carcinoma

30 May 2018

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Hereditary Renal-Cell Carcinoma Associated with a Chromosomal Translocation

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The FHIT gene 3p14.2 is abnormal in lung cancer.

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9572

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21 January 2018

1 reference

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BRCA1 mutations in primary breast and ovarian carcinomas.

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21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9572

FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing aberrations.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21380

Expression of reciprocal hybrid transcripts of HMGIC and FHIT in a pleomorphic adenoma of the parotid gland.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21380

The FHIT gene at 3p14.2 is abnormal in breast carcinomas

29 November 2018

1 reference

12 December 2020

Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog

1 reference

12 December 2020

Clinical and genetic studies of renal cell carcinomas in a family with a constitutional chromosome 3;8 translocation. Genetics of familial renal carcinoma

1 reference

12 December 2020

Aberrant FHIT transcripts in Merkel cell carcinoma

1 reference

12 December 2020

Evaluation of the FHIT gene in colorectal cancers

1 reference

12 December 2020

Involvement of multiple loci on chromosome 3 in renal cell cancer development

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9572

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1073/PNAS.95.16.9572

1 reference

1879858

ADS bibcode

1998PNAS...95.9572G

0 references

1879858

1 reference

1 reference

1 reference