The conserved KMN network constitutes the core microtubule-binding site of the kinetochore (Q24320105)

Kinetochore protein ndc-80 CELE_W01B6.9

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Kinetochore-binding protein 3 CELE_F26H11.1

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Kinetochore protein Nuf2 homolog CELE_R12B2.4

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author name string

Iain M Cheeseman

1

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Joshua S Chappie

2

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Elizabeth M Wilson-Kubalek

3

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Arshad Desai

A modular polycistronic expression system for overexpressing protein complexes in Escherichia coli

4

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language of work or name

English

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publication date

1 December 2006

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published in

Cell

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volume

127

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issue

5

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page(s)

983-97

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cites work

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Kinetochore-spindle microtubule interactions during mitosis

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Kinetochore microtubule dynamics and attachment stability are regulated by Hec1

1 reference

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The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment

1 reference

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The spindle checkpoint: tension versus attachment.

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The Formation, Structure, and Composition of the Mammalian Kinetochore and Kinetochore Fiber

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Kin I kinesins are microtubule-destabilizing enzymes

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Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections

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Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p

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Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling

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The vertebrate cell kinetochore and its roles during mitosis

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Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E

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A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1

1 reference

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7 January 2021

Drosophila CLASP is required for the incorporation of microtubule subunits into fluxing kinetochore fibres

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Molecular architecture of a kinetochore-microtubule attachment site

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The DASH complex and Klp5/Klp6 kinesin coordinate bipolar chromosome attachment in fission yeast

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Molecular organization of the Ndc80 complex, an essential kinetochore component

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Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore

1 reference

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The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation

1 reference

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Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation

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Implication of a novel multiprotein Dam1p complex in outer kinetochore function

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Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics

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The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.

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Interactions between Centromere Complexes inSaccharomyces cerevisiae

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Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites

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Measuring the stoichiometry and physical interactions between components elucidates the architecture of the vertebrate kinetochore

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Repeat motifs of tau bind to the insides of microtubules in the absence of taxol

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7 January 2021

KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans

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Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes

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A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension

1 reference

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The dynamic kinetochore-microtubule interface

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