X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase (Q24321294)

GOA release 2020-03-11

NAD binding

1 reference

GOA release 2020-03-11

Paul D Adams

16

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author name string

Thomas A Pauly

1

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Jennifer L Ekstrom

2

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David A Beebe

3

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Boris Chrunyk

4

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David Cunningham

5

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Matthew Griffor

6

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Ajith Kamath

7

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S Edward Lee

8

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Rebecca Madura

9

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Dewitt Mcguire

10

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Timothy Subashi

11

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David Wasilko

12

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Paul Watts

13

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Banavara L Mylari

14

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Peter J Oates

15

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Virginia L Rath

Structural consequences of sequence patterns in the fingerprint region of the nucleotide binding fold. Implications for nucleotide specificity

17

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language of work or name

English

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publication date

September 2003

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published in

Structure

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volume

11

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issue

9

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page(s)

1071-85

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cites work

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Crystal structure of the NADP(H)-dependent ketose reductase from Bemisia argentifolii at 2.3 A resolution

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7 January 2021

Comparison of the effects of inhibitors of aldose reductase and sorbitol dehydrogenase on neurovascular function, nerve conduction and tissue polyol pathway metabolites in streptozotocin-diabetic rats

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Orally-effective, long-acting sorbitol dehydrogenase inhibitors: synthesis, structure-activity relationships, and in vivo evaluations of novel heterocycle-substituted piperazino-pyrimidines

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Modelling studies on the binding of substrate and inhibitor to the active site of human sorbitol dehydrogenase

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7 January 2021

Expression, purification and preliminary crystallographic analysis of human sorbitol dehydrogenase

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The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

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7 January 2021

Three-dimensional structure of horse liver alcohol dehydrogenase at 2.4 Å resolution

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Molecular aspects of functional differences between alcohol and sorbitol dehydrogenases

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Effect of aldose reductase inhibition on nerve conduction and morphometry in diabetic neuropathy. Zenarestat Study Group

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A highly automated heavy-atom search procedure for macromolecular structures

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Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy: a 52-week multicenter placebo-controlled double-blind parallel group study

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Affinity purification and glucose specificity of aldose reductase from bovine lens.

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Long-term effect of epalrestat, an aldose reductase inhibitor, on the development of incipient diabetic nephropathy in Type 2 diabetic patients

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7 January 2021

Structural organization of the human sorbitol dehydrogenase gene (SORD)

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7 January 2021

Properties of sorbitol dehydrogenase and characterization of a reactive cysteine residue reveal unexpected similarities to alcohol dehydrogenases

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7 January 2021

Sorbitol dehydrogenase is a zinc enzyme

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7 January 2021

Crystal structure of sorbitol dehydrogenase

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Improved methods for building protein models in electron density maps and the location of errors in these models

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Zinc coordination in mammalian sorbitol dehydrogenase. Replacement of putative zinc ligands by site-directed mutagenesis.

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7 January 2021

Effect of pH on sheep liver sorbitol dehydrogenase steady-state kinetics

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7 January 2021

Reversible inhibition of sheep liver sorbitol dehydrogenase by thiol compounds

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Reversible inhibition of sheep liver sorbitol dehydrogenase by the antidiabetogenic drug 2-hydroxymethyl-4-(4-N,N-dimethylaminosulfonyl-1-piperazino) pyrimidine

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7 January 2021

The kinetic mechanism of sheep liver sorbitol dehydrogenase

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7 January 2021

Recent Advances in Zinc Enzymology

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Purification and characterization of human liver sorbitol dehydrogenase

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Sorbitol dehydrogenase inhibitors (SDIs): a new potent, enantiomeric SDI, 4-[2-1R-hydroxy-ethyl)-pyrimidin-4-yl]piperazine-1-sulfonic acid dimethylamide

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A sorbitol dehydrogenase inhibitor of exceptional in vivo potency with a long duration of action: 1-(R)-[4-[4-(4,6-dimethyl[1,3,5]triazin-2-yl)- 2R,6S-dimethylpiperazin-1-yl]pyrimidin-2- yl]ethanol

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Polyol pathway and diabetic peripheral neuropathy

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Processing of X-ray diffraction data collected in oscillation mode

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The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society

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7 January 2021

Chemical and biological evolution of nucleotide-binding protein

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7 January 2021

Glycerol dehydrogenase. structure, specificity, and mechanism of a family III polyol dehydrogenase

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7 January 2021

On the role of Glu-68 in alcohol dehydrogenase

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7 January 2021

Diabetic vascular dysfunction: links to glucose-induced reductive stress and VEGF.

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

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Hyperglycemic pseudohypoxia and diabetic complications.

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Global and societal implications of the diabetes epidemic

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